Caleb Finch, Professor
(Gerontology and Biological Sciences, and Anthropology)

Andrus Gerontology Center, Room 336
3715 McClintock Ave.
Los Angeles, CA 90089
Phone: (213) 740-1756
E-mail: cefinch@usc.edu
Personal Web Site: http://www-rcf.usc.edu/~cefinch/

Research

Cell biology, mechanisms controlling postnatal development and aging in man and other mammals, Alzheimer's disease, study of genomic controls of mammalian development and aging.

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Bio

Dr. Finch received his undergraduate degree from Yale in 1961, where he majored in biophysics. He continued his work in cell biology and received his Ph.D. from Rockefeller University in 1969. Dr. Finch has received most of the major awards in biomedical gerontology, including the Robert W. Kleemeier Award of the Gerontological Society of America in 1985, the Sandoz Premier Prize by the International Geriatric Association in 1995, and the Irving Wright Award of AFAR and the Research Award of AGE in 1999. He has directed the NIA-funded Alzheimer Disease Research Center since 1984. Dr. Finch became a University Professor in 1989, an honor held by seven other professors at USC who contribute to multiple fields. Dr. Finch supervises three predoctoral fellows and four postdoctoral fellows and two research faculty. He is a member of ten editorial boards. He has written over 350 articles. In 1990 he published a major intellectual synthesis of aging: Longevity, Senescence, and the Genome.

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Education

Yale University, New Haven, Connecticut B.S. 1961 Biophysics
Rockefeller University, New York, New York Ph.D. 1969 Cell Biology
Rockefeller University, New York, New York Post-Doc 1969-1970 Comparative Pathology
Cornell University Medical College Post-Doc 1970-1971 Neurobiology

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Recent Publications

Finch CE (1990) Longevity, Senescence, and the Genome. University of Chicago Press. Second printing, 1994.

Wachter K, Finch CE (1997) Between Zeus and the Salmon: The Biodemography of Longevity. Washington, D.C.: National Academy of Sciences.

Finch CE, Pike MC, Witten M (1990) Slow mortality rate accelerations during aging in animals approximate that of humans. Science 249:902-905.

Finch CE, Sapolsky RM (1999) The evolution of Alzheimer disease, the reproductive schedule, and apoE isoforms. Neurobiol Aging 20:407-428.

Klein WL, Krafft GA, Finch CE (2001) Targeting small Aß oligomers: the solution to an Alzheimer's disease conundrum? Trends Neurosci 24:219-224.

Finch CE (2002) Evolution and the plasticity of aging in the reproductive schedules in long-lived animals: the importance of genetic variation in neuroendocrine mechanisms. In: Hormones, brain, and behavior (Pfaff D, Etgen AA, Fahrbach S, Rubin R, eds.). San Diego, CA: Academic Press.

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Courses Taught

Gero 440 Biodemography of aging (with Eileen Crimmins)

Gero 519 Recent Advances in Neurobiology: The neurobiology and endocrinology of aging

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Awards and Honors

RW Kleemeier Award of the Gerontological Society of America, 1985; Brookdale Award for Contributions to Gerontology, 1985; Johns Hopkins – University of Maryland Lectureship in Reproductive Biology, 1987; Allied-Signal Incorporated Award for Achievement in Biomedical Research on Aging, 1988; Research Award of the American Aging Association, 1994; Sandoz Prize, Premier Award of the International Association of Gerontology, 1995; Ipsen Foundation Prize for Research on Longevity (Paris), 1996; American Federation of Aging Research, Irving Wright Award, 1999

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Professional Memberships

AAAS (Fellow, 1987)
Endocrine Society
Gerontological Society of America (Fellow, 1975)
Neuroendocrine Society
Psychogeriatric Society
Psychoneuroendocrine Society
Society for Neuroscience
Society for Study of Reproduction

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