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Caleb Finch Ph.D.
ARCO/ Keischnick Professor of Gerontology and Biological Science
and University Professor, Director, Gerontology Research Institute.
Cell biology, mechanisms controlling postnatal development and aging
in man and other mammals, Alzheimer's disease. *Chair, National
research Council Committee on Biodemography of Aging: Bringing Bioindicators
to household surveys. *Chair, Symposium on Slow Aging (SOSA), Sept
22-23, USC
Dr. Finch is a Professor of Gerontology and Biological Sciences, and a founding member of the Departments of Molecular Biology and Neurobiology. He also
holds adjunct appointments in the Dept of Psychology, Dept of Physiology
and Dept of Neurology. He is also one of USC's 12 University Distinguished Professors.
Dr. Finch's major research interest is the study of genomic controls
of mammalian development and aging.
He received his undergraduate degree from Yale in 1961, where he
majored in biophysics. He continued his work in cell biology and
received his Ph.D. from Rockefeller University in 1969. Dr. Finch
has received most of the major awards in biomedical gerontology,
including the Robert W. Kleemeier Award of the Gerontological Society
of America in 1985, the Sandoz Premier Prize by the International
Geriatric Association in 1995, and the Irving Wright Award of AFAR
and the Research Award of AGE in 1999. He has directed the NIA-funded
Alzheimer Disease Research Center since 1984. Dr. Finch became a
University Distinguished Professor in 1989, an honor held by twelve other professors
at USC who contribute to multiple fields. Dr. Finch supervises three
predoctoral fellows and four postdoctoral fellows and two research
faculty. He is a member of ten editorial boards. He has written
over 350 articles. In 1990 he published a major intellectual synthesis
of aging: Longevity, Senescence, and the Genome.
In 1995, Dr. Finch and Robert Ricklefs published Aging: A Natural
History ( Scientific American Library Series) for the general public.
It has been translated into five different languages. In 2000, Chance, Development, and Aging was co-authored with Thomas Kirkwood, Oxford Press . His most recent book, single authored, is The Biology of Human Longevity. Inflammation, Nutrition, and Aging in the Evolution of Lifespans. Academic Press 2007. His latest
book, co-authored with Thomas Kirkwood was published by Oxford in
2000: Chance, Development, and Aging.
Most recent papers are:
Finch CE. Update on slow aging and negligible senescence--a
mini-review.Gerontology. 2009;55(3):307-13.
-PubMed
Finch CE.The neurobiology of middle-age has arrived. Neurobiol Aging. 2009;
30(4):515-20; discussion 530-33. -PubMed
Wong AM, Rozovsky I, Arimoto JM, Du Y, Wei M, Morgan TE, Finch CE.
Progesterone influence on neurite outgrowth involves microglia.
Endocrinology. 2009; 150(1):324-32. -PubMed
Faghihi MA, Modarresi F, Khalil AM, Wood DE, Sahagan BG, Morgan TE,
Finch CE, St Laurent G 3rd, Kenny PJ, Wahlestedt C.Expression of a noncoding RNA
is
elevated in Alzheimer's disease and drives rapid feed-forward regulation
of
beta-secretase.Nat Med. 2008;14(7):723-30. -PubMed
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