Caleb Finch Ph.D.
ARCO/ Keischnick Professor of Gerontology and Biological Science
and University Professor, Director, Gerontology Research Institute.
Cell biology, mechanisms controlling postnatal development and aging
in man and other mammals, Alzheimer's disease. *Chair, National
research Council Committe on Biodemography of Aging: Bringing Bioindicators
to household surveys. *Chair, Symposium on Slow Aging (SOSA), Sept
22-23, USC
Research and Grants
Alzheimer Disease Research Center (ADRC)
Principal Investigator : HC Chui
Associate Director : CE Finch
The ADRC project focuses on the molecular and cellular analysis of changes during
Alzheimers disease and on clinical methods for early detection and the identification of
subtypes. No overlap. No adjustment necessary.
Training in Endocrinology and Neurobiology of Aging (NIH/NIA)
Principal Investigator : CE Finch
The training grant provides pre and post doctoral training for research careers on
basic mechanisms in the neural and endocrine changes of aging and related clinical
disorders such as Alzheimers disease. No overlap. No adjustment necessary.
Models of Estrogen Interactions with Alzheimer Disease
Principal Investigator : CE Finch
The estrogen project project aims are to conduct experiments on rodent models in vivo
and in vitro to analyze mechanisms by which estrogens interact with neurons and glia
to modify synaptic plasticity. No overlap. No adjustment necessary
Caloric Restriction and Inflammatory Mechanisms
Principal Investigator: CE Finch
Alzheimer Association, Temple Award
This study will examine if caloric restriction can attenuate inflammatory changes during
aging in transgenic mouse models of Alzheimer disease. No overlap. No adjustment
necessary.
ApoJ, (Clusterin) in Alzheimer Disease and Aging
Principal Investigator : CE Finch
The ApoJ project aims are to study the interactions of A beta with apoJ and apoE
and their expression and to study the regulation of apoJ by hormones. No overlap.
No adjustment necessary.
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