Todd Morgan, Ph.D.
Research Associate Professor of Gerontology.
Molecular mechanisms underlying normal brain aging and Alzheimer's disease: Dietary, inflammatory and hormonal contributions.

Research and Grants

Caloric Restriction and Inflammatory Mechanisms
Alzheimer Association, Temple Award
CE Finch, (PI) TE Morgan, (Co-Principal Investigator)
This study examines if caloric restriction can attenuate inflammatory changes during aging in transgenic mouse models of Alzheimer disease.

Models of Estrogen Interactions with Alzheimer Disease
CE Finch (PI) TE Morgan, (Co-Investigator)
The estrogen program project aims are to conduct experiments on rodent models in vivo and in vitro to analyze mechanisms by which estrogens interact with neurons and glia to modify synaptic plasticity.

Completed Research Support

ApoJ, (Clusterin) in Alzheimer Disease and Aging
CE Finch (PI) TE Morgan (Co-Investigator)
The ApoJ project aims are to study the interactions of A beta with apoJ and apoE expression using in vivo models of Alzheimer disease and primary cell cultures.

Clusterin Regulation and Activity During Neurodegeneration
TE Morgan (Principal Investigator)
Alzheimer Association
This clusterin (ApoJ) project examines regulation of clusterin expression by cytokines and the bioactivity of clusterin in vivo and in vitro.

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