Full text of The NCBI Handbook. Bethesda (MD): National Library of Medicine (US), NCBI; 2002 Nov. is provided through the NCBI Bookshelf.
An online book, written by NCBI staff, that discusses the many resources available at NCBI. Each chapter is devoted to one service; after a brief overview on using the resource, there is an account of how the resource works, including topics such as how data are included in a database, database design, query processing, and how the different resources relate to each other.