The American Journal of Medical Genetics states its Aim & Scope as publishing 40 issues a year on all biological and medical aspects of genetic disorders and birth defects for physicians, medical geneticists, and associated professionals. In addition to Part A, AJMG also publishes two other parts:
Part B: Neuropsychiatric Genetics, covering experimental and clinical investigations of the genetic mechanisms underlying neurologic and psychiatric disorders.
Part C: Seminars in Medical Genetics, guest-edited collections of thematic reviews of topical interest to the readership of AJMG.
The Journal's primary purpose is to report original research in the following areas:
Biochemical Genetics, including newborn screening, carrier detection, and the metabolic dysplasia and malformation syndromes;
Cancer Genetics and Cancer Cytogenetics, including experimental and molecular approaches;
Clinical Genetics, including descriptions of new syndromes, new causal and pathogenetic insights into known syndromes, advances in genetic counseling, nosology, anthropometry, and anthropology, including dermatoglyphics;
Clinical Molecular Genetics, including linkage, mapping, and gene sequencing;
Formal Genetics, including quantitative, population, and epidemiological genetics;
Molecular Cytogenetics, including delineation of syndromes due to chromosomal aberration;
Neuropsychiatric Genetics, including reports on novel research on the genetic mechanisms underlying psychiatric and neurological disorders;
Reproductive Genetics, including prenatal diagnosis and the genetics of prenatal and perinatal death in humans.