Treating heart failure is one of the most common challenges facing contemporary cardiovascular medicine. It is associated with many cardiac disease states, including coronary artery disease, valvular heart disease, and cardiomyopathy, and is even associated with pregnancy. A clinical program has been established at USC for the diagnosis, evaluation, and management of heart failure. Clinical care can include outpatient treatment, at-home infusion therapy, and device therapy as well as evaluation for surgical ventricular restoration, potential valve repairs, heart transplantation, and participation in the STICH trial. With its complement of advanced diagnostic techniques and instrumentation, the Division of Cardiovascular Medicine provides heart failure patients with expert diagnoses, treatment, and follow-up.