Baruch Frenkel

 D.M.D.

Assistant Professor

Keck School of Medicine
Department of  Orthopaedics

Glucocorticoids (GC) are used in the treatment of autoimmune and inflammatory diseases, such as asthma and rheumatoid arthritis. One major side effect of GC therapy is osteoporosis. Dr. Frenkel is investigating the transcriptional activities of the glucocorticoid receptor (GR) in osteoblasts. He is interested in both the trans-activation of promoters containing GR binding, sites, and the trans-repression of promoters containing cognate elements for transcription factors capable of protein-protein interactions with the GR.

 

 

 

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