Paul Denny

Ph.D.

Professor

School of Dentistry

Mucins from saliva are a class of glycoproteins whose bio-activities range from formation of protective coatings to aggregation and/or inactivation of specific strains of viruses and oral bacteria. Dr. Denny’s long term goal is to provide a rationale for developing treatments to reverse losses of mucin from salivary glands and saliva such as observed to accompany aging in humans and mice. An understanding of the fundamental processes surrounding mucin synthesis and glycosylation is the key to revealing the origins of the aging-related losses and to development of appropriate treatment responses.

 

 

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