Henry M. Sucov

 Ph.D.

Associate Professor

Keck School of Medicine
Department of Biochemistry and Molecular Biology
Institute for Genetic Medicine

His long lerm research is based in genetic strategies (primarily gene targeting approaches in mice) which have significantly broadened research in cardiovascular developmental biology by illuminating new pathways involved in heart development and by allowing the genetic evaluation of pathways that have previously been implicated in these events. A second area of interest involved the vitamin A derivative retinoic acid (RA) and related compounds (retinoids) which are utilized as signaling molecules in a diverse array of developmental and physiological regulatory processes, including many important in the developing and mature nervous system. Dr. Maxson, Snead and Sucov collaborate on a project to produce a Cre-recombinase mouse driven by domains of the Msx promoter that specify tissue restricted expression of Cre. to neural crest cells.

 

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