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Research
& Professional Experience
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2006-present |
Research Associate, Center for Craniofacial Molecular Biology, School
of Dentistry, University of Southern California, Los Angeles, CA |
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2004-2006 |
Postdoctoral Research Associate, Center for Craniofacial Molecular Biology, School
of Dentistry, University of Southern California, Los Angeles, CA |
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1999-2004 |
Research Assistant, Center for Craniofacial Molecular Biology, School
of Dentistry, University of Southern California, Los Angeles, CA |
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1998-1999 |
Dentist, The Oral Department of Beijing Children’s Hospital, China |
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Publications
Hosokawa
R, Urata M, Han J, Zehnaly A., Bringas Jr P, Nonaka K, Chai Y. (2007). TGF-beta
mediated Msx2 expression controls occipital somites-derived caudal region of
skull development. Dev. Biol. 310(1):140-53.
Han
J, Ishii M, Bringas P Jr, Maas RL, Maxson RE Jr, Chai1 Y. (2007). Concerted
action of Msx1 and Msx2 in regulating cranial neural crest cell differentiation
during frontal bone development. Mechanisms of Development
124(9-10):729-45
Xu
X, Han J, Ito Y, Bringas P Jr., Urata MM, Chai Y. (2006). Cell
autonomous requirement for Tgfbr2 in the disappearance of medial edge epithelium
during palatal fusion. Dev. Biol. 297(1):238-48.
Ishii
M, Han J, Yen HY, Sucov HM, Chai Y, Maxson RE Jr. (2005). Combined
deficiencies of Msx1 and Msx2 cause impaired patterning and survival of the
cranial neural crest. Development. 132(22):4937-50.
Sasaki
T, Ito Y, Xu X, Han J, Bringas P Jr, Maeda T, Slavkin HC, Grosschedl R, Chai Y.
(2005). LEF1
is a critical epithelial survival factor during tooth morphogenesis. Dev.
Biol.
278,130-143.
Ito
Y, Yeo JY, Chytil A, Han J, Bringas P Jr, Nakajima A, Shuler CF, Moses HL, Chai
Y. (2003). Conditional
inactivation of TGF-beta IIR in cranial neural crest causes
cleft palate and calvaria defects.
Development 130, 5269-5280.
Han
J., Ito Y., Yeo J., Sucov H.M., Maas R., and Chai Y. (2003) Cranial neural
crest-derived mesenchymal proliferation is regulated by Msx1-mediated p19INK4d
expression during odontogenesis. Dev.
Biol. 261, 183-196.
Chai
Y., Ito Y., and Han J. (2003) TGF-beta signaling and its functional significance
in regulating the fate of cranial neural crest cells. Crit. Rev. Oral Biol.
Med. 14, 78-88
Zhang
Y, Wang S, Song Y, Han J, Chai Y, Chen Y. (2003). Timing
of odontogenic neural crest cell migration and tooth-forming capability in mice. Dev. Dyn. 226,
713-718
Xu
X, Jeong L, Han J, Ito Y, Bringas P Jr, Chai Y. (2003). Developmental
expression of Smad1-7 suggests critical function of TGF-beta/BMP signaling in
regulating epithelial-mesenchymal interaction during tooth morphogenesis.
Int J Dev Biol 47(1):31-9
Chai
Y, Jiang X, Ito Y, Bringas P Jr, Han J, Rowitch DH, Soriano P, McMahon
AP, Sucov HM (2000).
Fate of the mammalian cranial neural crest during tooth and mandibular
morphogenesis. Development, 127,1671-1679.
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