CSA113, HSC 9062 (323)442-3404 Voice (323)442-2981 Fax qunzhouz@usc.edu

Qunzhou Zhang

Ph.D.

Research Associate

Education

Research & Professional Experience

Academic Honors and Awards

Publications

Zhang Q, Tang X, Zhang ZF, Velikina R, Shi S, Le AD. (2007) Nicotine induces hypoxia-inducible factor-1alpha expression in human lung cancer cells via nicotinic acetylcholine receptor-mediated signaling pathways. Clin Cancer Res. 13(16):4686-94.

Tang X, Zhang Q, Nishitani J, Brown J, Shi S, Le AD. (2007).  Overexpression of human papillomavirus type 16 oncoproteins enhances hypoxia-inducible factor 1 alpha protein accumulation and vascular endothelial growth factor expression in human cervical carcinoma cells. Clin Cancer Res. 13(9):2568-76.

Zhang Q, Kelly AP, Wang L, French SW, Tang X, Duong HS, Messadi DV, Le AD. (2006).  Green Tea Extract and (-)-Epigallocatechin-3-Gallate Inhibit Mast Cell-Stimulated Type I Collagen Expression in Keloid Fibroblasts via Blocking PI-3K/Akt Signaling Pathways. J Invest Dermatol. 126(12):2607-13

Zhang Q, Tang X, Lu Q, Zhang Z, Rao J, Le AD. (2006).  Green tea extract and (-)-epigallocatechin-3-gallate inhibit hypoxia- and serum-induced HIF-1alpha protein accumulation and VEGF expression in human cervical carcinoma and hepatoma cells. Mol Cancer Ther. 5(5):1227-38. 

Duong HS, Zhang QZ, Le AD, Kelly AP, Kamdar R, Messadi DV. (2006). Elevated prolidase activity in keloids: correlation with type I collagen turnover. Br J Dermatol. 154(5):820-8.

Zhang Q, Oh CK, Messadi DV, Duong HS, Kelly AP, Soo C, Wang L, Le AD. (2006). Hypoxia-induced HIF-1 alpha accumulation is augmented in a co-culture of keloid fibroblasts and human mast cells: involvement of ERK1/2 and PI-3K/Akt. Exp Cell Res. 312(2):145-55.

Duong HS, Le AD, Zhang Q, Messadi DV. (2005).  A novel 3-dimensional culture system as an in vitro model for studying oral cancer cell invasion. Int J Exp Pathol. 86(6):365-74.

Zhang Q, Tang X, Lu QY, Zhang ZF, Brown J, Le AD. (2005). Resveratrol inhibits hypoxia-induced accumulation of hypoxia-inducible factor-1alpha and VEGF expression in human tongue squamous cell carcinoma and hepatoma cells. Mol Cancer Ther. 4(10):1465-74.

Chau CH, Clavijo CA, Deng HT, Zhang Q, Kim KJ, Qiu Y, Le AD, Ann DK. (2005). Etk/Bmx mediates the expression of stress-induced adaptive genes, VEGF, PAI-1, and iNOS via multiple signaling cascades in different cell systems. Am J Physiol Cell Physiol.  289(2):C444-54

Zhang Q, Zhang ZF, Rao JY, Sato JD, Brown J, Messadi DV, Le AD. (2004). Treatment with siRNA and antisense oligonucleotides targeted to HIF-1alpha induced apoptosis in human tongue squamous cell carcinomas. Int J Cancer. 111(6):849-57

Zhou JJ, Chen ML, Zhang QZ, Hu JK, Wang WL.  (2004). Co-expression of cholecystokin-B/gastrin receptor and gastrin gene in human gastric tissues and gastric cancer cell line.  World J Gastroenterology, 10(6): 791-794

Zhou JJ, Hu JK, Chen Z, Wang WL, Zhang QZ, Chen M. (2004). Human gastric tissues coexpress two different splicing cholecystokinin-B/gastrin receptors.  Sheng Wu Yi Xue Gong Cheng Xue Za Zhi. 21(3): 440-443

Messadi DV, Duong HS, Zhang Q, Kelly AP, Tuan TL and Le AD. (2004).  Activation of NFKappaB signal pathways in keloid fibroblasts. Arch. Derm. Research, 296(3):125-33

Mohamed KM, Le A, Duong H, Wu Y, Zhang Q, Messadi DV. (2004). Correlation between VEGF and HIF-1alpha expression in human oral squamous cell carcinoma.  Exp Mol Pathol. 76(2):143-52

Wu Y, Zhang Q, Ann DK, Akhondzadeh A, Duong HS, Messadi DV, Le AD. (2004). Increased vascular endothelial growth factor may account for elevated level of plasminogen activator inhibitor-1 via activating ERK1/2 in keloid fibroblasts. Am J Physiol Cell Physiol. 286(4):C905-12

Zhang Q, Wu Y, Chau CH, Ann DK, Bertolami CN, Le AD.  (2004). Crosstalk of hypoxia-mediated signaling pathways in upregulating plasminogen activator inhibitor-1 expression in keloid fibroblasts.  J Cell Physiol., 199:89-97.

Le AD, Zhang Q, Wu Y, Messadi DV, Akhondzadeh A, Nguyen AL, Aghaloo TL, Kelly AP, Bertolami CN. (2004). Elevated vascular endothelial growth factor in keloids: relevance to tissue fibrosis. Cells Tissues Organs, 176(1-3): 87-94.

Zhang Q, Wu Y, Ann DK, Messadi DV, Tuan TL, Kelly AP, Bertolami CN, Le AD. (2003).  Mechanisms of hypoxic regulation of plasminogen activator inhibitor-1 gene expression in keloid fibroblasts.  J Invest Dermatol 121:1005-1012.

Zhang QZ, Chen ML, Li RH.  (2003). Effects of hCG on the in vitro proliferation of human gastric adenocarcinoma cell line (SGC-7901 cells).  Sichuan Da Xue Xue bao Yi Xue Ban, 34(4): 678-679.

Zhang QZ, Li RH, Chen ML, Wu ZF. (2002). Effects of human   chorionic gonadotropin on intracellular signal transduction in human gastroadenocarcinma SGC-7901 cells. Chin J Digest Diseases, 22: 470-473.

Zhang QZ, Chen ML. (2000).  Effects of hCG on the cAMP levels in human   gastric cancer cells. J  West China University of Med Sci; 31(3): 312-314. 

Zhang QZ, Zhou KY, Cai KR, Ling GX. (1998). Changes of  Oncogen Expressions in Nasopharyngeal Carcinoma Cells During Apoptosis. Chin J  Histochem Cytochem, 7(2): 168-172

Zhang QZ, Zhou KY, Ling GX. (1997).  Apoptosis in Human nasopharyngeal Carcinoma Cell Lines Induced by DNA Topo I Inhibitor. Chin J Otolaryngol, 32 (6): 332-3352. 

Zhang QZ, Zhou KY, Ling GX. (1997). Apoptosis of Leukemia Cells Induced by adenosine. Chin J  Hemotol, 18(5):266 

Last Updated: 03/18/08

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