CSA 113, HSC 9062
(323)442-3403 Voice
(323)442-2981 Fax
susansmi@usc.edu



Susan Smith

B.Sc.

Research Technician III/Supervisor

Education    Experience    Publications   


Education

INSTITUTION AND LOCATION

DEGREE

YEAR(s)

FIELD OF STUDY

University of Chicago

A.B.

1984

Biology


Research & Professional Experience

1996-present

Research Technician III/Supervisor, Center for Craniofacial Molecular Biology, School of dentistry, University of Southern California, Los Angeles, CA

1992-1996

Research Technician, Division of Research immunology Children’s Hospital, Los Angeles

1990-1992

Research Technician, Division of Pediatric Infectious Diseases Children’s Hospital, University of Washington

1986-1989

Research Technician, Division of Pediatric Infectious Diseases, Stanford University

1984-1986

Research Technician, Division of Gastroenterology University of Chicago


Publications

Lee MK, Pardoux C, Hall MC, Lee PS, Warburton D, Qing J, Smith SM, Derynck R.  (2007).  TGF-beta activates Erk MAP kinase signalling through direct phosphorylation of ShcA. EMBO J.;26(17):3957-67.

Smith SM, Crowe DL, Lee MK. (2006). beta1 integrins modulate p66ShcA expression and EGF-induced MAP kinase activation in fetal lung cells. Biochem Biophys Res Comm. 342(4):909-918

Lee MK, Pryhuber GS, Schwarz MA, Smith SM, Pavlova Z, Sunday ME. (2005). Developmental regulation of p66Shc is altered by bronchopulmonary dysplasia in baboons and humans. Am J Respir Crit Care Med. 171:1384-94.

Tefft D, Lee M, Smith S, Crowe DL, Bellusci S, Warburton D. (2002). mSprouty2 inhibits FGF10-activated MAP kinase by differentially binding to upstream target proteins. Am J Physiol Lung Cell Mol Physiol 283(4):L700-L706

Crowe DL, Brown TN, Kim R, Smith SM, Lee MK (2000). A c-fos/Estrogen receptor fusion protein promotes cell cycle progression and proliferation of human cancer cell lines. Mol Cell Biol Res Commun 3(4):243-8

Tefft JD, Lee M, Smith S, Leinwand M, Zhao J, Bringas P Jr, Crowe DL, Warburton D (1999). Conserved function of mSpry-2, a murine homolog of Drosophila sprouty, which negatively modulates respiratory organogenesis. Curr Biol 9(4):219-22

Schwarz M, Lee M, Zhang F, Zhao J, Jin Y, Smith S, Bhuva J, Stern D, Warburton D, Starnes V (1999). EMAP II: a modulator of neovascularization in the developing lung. Am J Physiol 276(2 Pt 1):L365-75

Zhao J, Lee M, Smith S, Warburton D (1998). Abrogation of Smad3 and Smad2 or of Smad4 gene expression positively regulates murine embryonic lung branching morphogenesis in culture. Dev Biol 194(2):182-95

Lee MK, Zhao J, Smith SM, Tefft JD, Bringas P, Hwang C, Warburton D (1998). The Shc 66 and 46 kD isoforms are differentially downregulated at parturition in the fetal mouse lung. Pediatr Res 44(6):850-9

Taylor N, Jahn T, Smith S, Lamkin T, Uribe L, Liu Y, Durden DL, Weinberg K (1997). Differential activation of the tyrosine kinases ZAP-70 and Syk after Fc gamma RI stimulation. Blood 89(2):388-96

Taylor N, Uribe L, Smith S, Jahn T, Kohn DB, Weinberg K (1996). Correction of interleukin-2 receptor function in X-SCID lymphoblastoid cells by retrovirally mediated transfer of the gamma-c gene. Blood 87:3103-3107.

Taylor N, Bacon KB, Smith S, Jahn T, Kadlecek TA, Uribe L, Kohn DB, Gelfand EW, Weiss A, Weinberg K (1996). Reconstitution of T cell receptor signaling in ZAP-70-deficient cells by retroviral transduction of the ZAP-70 gene. J Exp Med 184(5):2031-6

Tamura GS, Kuypers JM, Smith S, Raff H, Rubens CE (1994). Adherence of group B streptococci to cultured epithelial cells: roles of environmental factors and bacterial surface components. Infect Immun. 62:2450-2458.

Hulse ML, Smith S, Chi EY, Pham A, Rubens CE (1993). Effect of type III group B streptococcal capsular polysaccharide on invasion of respiratory epithelial cells. Infect Immun 61:4835-4841.

Rubens CE, Smith S, Hulse M, Chi EY, van Belle G (1992). Respiratory epithelial cell invasion by group B streptococci. Infect Immun 60:5157-5163.

Arvin AM, Sharp M, Smith S, Koropchak CM, Diaz PS, Kinchington P, Ruyechan W, Hay J (1991). Equivalent recognition of a varicella-zoster virus immediate early protein (IE62) and glycoprotein I by cytotoxic T lymphocytes of either CD4+ or CD8+ phenotype. J lmmunol 146:257-264.

Diaz PS, Smith S, Hunter E, Arvin AM (1989). T lymphocyte cytotoxicity with natural varicella-zoster virus infection and after immunization with live attenuated varicella vaccine. J Immunol. 142:636-641.

Diaz PS, Smith S, Hunter E, Arvin AM (1988). Immunity to whole varicella-zoster virus antigen and glycoproteins I and p170: relation to the immunizing regimen of live attenuated varicella vaccine. J Infect Dis 158:1245-1252.

Last Updated: 10/10/07

 

 

 

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