University of Southern California


Yi-Bu Chen, Ph.D, M.S.
Program Coordinator

NML Bioinformatics Services

Norris Medical Library
2003 Zonal Avenue
Los Angeles, CA 90089-9130
(323) 442-3309


Library Responsibilities

  • Workshop instruction on bioinformatics databases and software
  • Consultation on bioinformatics and related online resources
  • Development and maintenance of Norris Library webpage on Bioinformatics and Molecular Biology Resources and Services
  • Delivery of regular updates on new online bioinformatics resources via electronic mailing lists

Contact me for questions or instruction regarding

  • bioinformatics workshop content and schedules
  • finding online databases and software tools relevant to your specific research needs
  • applying bioinformatics tools in various stages of your research
  • analyzing and interpreting molecular biology data

Liaison for the following:

Professional Information

PhD, Biology, Biology Department, Rensselaer Polytechnic Institute, Troy, NY, 1998
MS, Biological Oceanography, Institute of Marine Sciences, University of Southern Mississippi, MS, 1994
BS, Marine Biology, Department of Biology, Ocean University of China, Qingdao, P.R. China, 1984

Information Specialist in Molecular Biology, Health Sciences Library System, University of Pittsburgh, PA, 2005 - 2007

Postdoc and Research Associate, Institute of Marine and Coastal Science, Rutgers University, NJ, 1998 - 2004

  • Leung Y, Kandyba E, Chen YB, Seth Ruffins, and Kobielak K.  Label-Retaining Cells (LRCs) with myoepithelial characteristic from the proximal acinar region define stem cells in the sweat gland.  2013 PLOS ONE  In press.
  • Meng L, Chen YB, and Clintworth WA.  Expanding roles in a library-based bioinformatics service program: a case study.  2013.  Journal of Medical Library Association. 101(4):303-309.
  • Kandyba E, Leung Y, Chen YB, Widelitz R, Chuong CM, and Kobielak K.  2013.  Competitive balance of intrabulge BMP/Wnt signaling reveals a robust gene network ruling stem cell homeostasis and cyclic activation.  Proc Natl Acad Sci USA. 110(4):1351-1356
  • Ishii M, Arias AC, Liu L, Chen YB, Bronner ME, and Maxson RE.  2012.  A stable cranial neural crest cell line from mouse.  Stem Cells Dev. 21(17):3069-80.
  • Cao C, Chen YB, Masood R, Sinha UK, and Kobielak A.  2012.  α-Catulin marks the invasion front of squamous cell carcinoma and is important for tumor cell metastasis.   Mol Cancer Res. 10(6):892-903
  • Dai Y, Guo L, Li M, and Chen YB. 2012.  Microarray Я US: a user-friendly graphical interface to Bioconductor tools that enables accurate microarray data analysis and expedites comprehensive functional analysis of microarray results.  BMC Res Notes 5:282
  • Lacruz RS, Smith CE, Bringas P Jr, Chen YB, Smith SM, Snead ML, Kurtz I, Hacia JG, Hubbard MJ, and Paine ML.  2012.  Identification of novel candidate genes involved in mineralization of dental enamel by genome-wide transcript profiling.  J. Cell Physiol. 227(5):2264-75.
  • Chimge NO, Baniwal SK, Little GH, Chen YB, Kahn M, Tipathy D, Borok Z, and Frenkel B. 2011.  Regulation of breast cancer metastasis by Runx2 and estrogen signaling: the role of SNAI2.  Breast Cancer Res. 13(6):R127
  • Lacruz RS, Smith CE, Chen YB, Snead ML, Hacia JG, Hubbard MJ, and Paine ML.  2011.  Gene-expression analysis of early- and late-maturation-stage rat enamel organ.  Eur. J. Oral Sci. 119 Suppl 1:149-57.
  • Berman-Frank I, Chen YB, Gao Y, Fennel K, Follows MJ, Milligan AJ, and Falkowski PG. 2008.  Feedbacks Between the Nitrogen, Carbon and Oxygen Cycles.  In DG Capone et al. (eds): “Nitrogen in the Marine Environment” 2nd version.  Elsevier Academic Press.
  • Chen YB, Chattopadhyay A, Bergen P, Gadd C and Tannery N. 2007. The online Bioinformatics resources collection at the University of Pittsburgh Health Sciences Library System - A one-stop gateway to online Bioinformatics databases and software tools. Nucleic Acids Research 2007 Database Issue, 35:D780-D785 Click to Download PDF
  • Giordano M, Chen YB, Koblizek M, and Falkowski PG. 2005. Regulation of nitrate reductase in Chlamydomonas reinhardtii by the redox state of the plastoquinone pool. European Journal of Phycology. 40:345-352 Click to Download PDF
  • Berman-Frank I, Chen YB, Gerchman Y, Dismukes GC and Falkowski PG. 2005. Inhibition of nitrogenase by oxygen in marine cyanobateria controls the global nitrogen and oxygen cycles. Biogeosciences Discussions. 2:1-13 Click to Download PDF
  • Chen YB, Durford DG, Koblizek M, Falkowski PG. 2004. Plastic regulation of Lhcb1 transcription in the chlorophyte alga Dunaliella tertiolecta. Plant Physiology. 136(3):3737-3750 Click to Download PDF
  • Falkowski PG and Chen YB. 2003. Photoacclimation of light harvesting systems in eukaryotic algae. In BR Green and WW Parson (eds): "Light-harvesting antennas in photosynthesis". Dordrecht, Boston, Kluwer Academic Publishers.
  • Berman-Frank, I, P. Lundgren, Chen YB, H Kupper, Z Kolber, B Bergman, and PG Falkowski. 2001. Segregation of nitrogen fixation and oxygenic photosynthesis in the marine cyanobacteria Trichodesmium. Science 294:1534-1537 Click to Download PDF
  • Dominic B, S Zani, Chen YB, MT Mellon and JP Zehr. 2000. Organization of nif genes of nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. Journal of Phycology 36:693-701 Click to Download PDF
  • Chen YB, B Dominic, S Zani, MT Mellon, and JP Zehr. 1999. Expression of photosynthesis genes in relation to nitrogen fixation in the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. Plant Molecular Biology 41:89-104 Click to Download PDF
  • Chen YB, B Dominic, MT Mellon, and JP Zehr. 1998. Circadian rhythm of nitrogenase gene expression in the filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101. Journal of Bacteriology. 180:3598-3605 Click to Download PDF
  • Dominic, B, Chen YB, and JP Zehr. 1998. Cloning and transcriptional analysis of the nifUHDK genes of Trichodesmium sp. IMS 101 reveals stable nifD, nifDK, and nifK transcripts. Microbiology (UK) 144:3359-3368 Click to Download PDF
  • Zehr JP, B Dominic, Chen YB, MT Mellon and JC Meeks. 1998. Nitrogen fixation in the marine cyanobacteria Trichodesmium: a challenging model for ecology and molecular biology. In GA Peschek, W Loffelhardt, and G Schmetterer (eds.) "Phototrophic Prokaryotes". Plenum Press, New York
  • Chen YB, JP Zehr, and MT Mellon. 1996. Growth and nitrogen fixation of the diazotrophic filamentous nonheterocystous cyanobacterium Trichodesmium sp. IMS 101 in defined media: evidence for a circadian rhythm. Journal of Phycology 32:916-923 Click to Download PDF
Revised 9/16/13


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