University of Southern California

Multiple Sequence Alignment and Motif Discovery

MultiPipMaker
MultiPipMaker is a multiple sequence alignment tool. Thhis program can be used with this web interface.

ClustalW / ClustalX
ClustalW is a multiple sequence alignment program from EBI. The windows version and unix version stand-alone program can be downloaded from EBI.

ClustalX is the GUI version of ClustalW. The Windows version and UNIX version stand-alone program can be downloaded from EBI.

T-COFFEE
T-COFFEE is a multiple sequence alignment program. It is slower but more accurate than other programs for sequences with less than 30% identity. This program is used with this web interface.

DIALIGN
DIALIGN is a DNA and protein sequence alignment program based on segment-to-segment comparison. The following are two DIALIGN web interfaces:
http://bibiserv.techfak.uni-bielefeld.de/dialign/submission.html,
http://bioweb.pasteur.fr/seqanal/interfaces/dialign2-simple.html.
The program can also be used with this stand-alone version.

Blocks Server
Blocks Server is a service for biological sequence analysis at the Fred Hutchinson Cancer Research Center in Seattle.

HMMER
HMMER is a freely distributable implementation of profile hidden Markov models (profile HMMs) software for protein sequence analysis.

MEME
MEME is a tool for discovering motifs in a group of related DNA or protein sequences.

MOTIF
MOTIF is a service for searching protein and nucleic acid sequence motifs.

PatScan
PatScan is a pattern matcher which searches protein or nucleotide (DNA, RNA, tRNA etc.) sequence archives for instances of a pattern which you input.


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