Access Policy
The Norris Medical Library has licensed Ingenuity Pathway Analysis (IPA) with 1 concurrent user seat. The software is available to all registered USC users, free of charge. Interested users may find access policy and registration request here.
Main Applications
- IPA Core Analysis: Identify signaling and metabolic pathways, molecular networks, and biological processes that are most significantly perturbed in a dataset of interest.
- IPA-Metabolomics: Gain biological insight into cell physiology and metabolism from metabolite data.
- IPA-Tox: Analyze toxicity and safety of candidate compounds to better understand pharmacological response, drug mechanism of action, and mechanism of toxicity.
- IPA-Biomarker: Identify the most promising and relevant biomaker candidates within experimental datasets.
- Path Designer: Transform customized networks and pathways into publication-quality pathway graphics.
Noteworthy Features
- All-in-one web-based application provides easy and flexible accesses, as well as facilitates collaboration and results sharing.
- High quality, human curated knowledge database for functional and systematic analysis of data derived from gene expression and SNP microarrays, metabolomics and proteomics experiments, and smaller-scale experiments that generate gene lists.
- Enables search for targeted information on genes, proteins, chemicals, and drugs, and build interactive models of your experimental systems.
- Extensive library of well-characterized signaling and metabolic pathways offer a starting point for exploration and a bridge between novel discovery and known biology. Layer in novel insights, drugs, and 'omics data.
- Direct import of gene lists from microarray analysis software such as Partek Genomic Suite allows seamless integration of high throughput omics data.
- Accepts data from various experimental platforms such as gene expression, proteomics, genotyping, sIRNA, and Metabolimics. Supports all major array platforms.
- Extensive knowledge database on model organisms human, mouse, rat and canine. Additional species supported via ortholog mapping.
- Interactively links external major databases in NCBI and other sources.
- Supports Windows (XP and Vista) and Macintosh OS, and fully compatible with major web browsers.
Workshops on IPA
On-site Ingenuity System Training, multiple sessions, one day event (Fall 2008, to be arranged)
Introduction to IPA (Fall 2008, to be arranged)
Tutorials and other user support documentations
- General information and overview of IPA
- IPA Library
The library contains a wide array of user support resources, including "Ingenuity Databases", "IPA Application Notes and White Papers", "Web-based Video Seminars", st.
Questions and Help
Send your questions or request a consultation on IPA related topics:
Yi-Bu Chen, Ph.D., Bioinformatics Specialist
Email: yibuchen (at) usc.edu Phone: 323-442-3309
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