University of Southern California

NCBI Protein Databases

Protein
The Entrez Protein Database is a collection of protein sequences from a variety of sources, including SwissProt, PIR, PRF, PDB, and translations from annotated coding regions in GenBank and RefSeq.

RefSeq
The Reference Sequence (RefSeq) is a biologically non-redundant collection of DNA, RNA, and protein sequences. RefSeq provides one example for each biological molecule per organism. The alternatively spliced transcripts that share identical exons have different entries in RefSeq.

The common Refseq accession prefix
Accession prefix
    Molecular type
NC_
    Complete genomic molecule
NT_
    Genomic contig
NM_
    mRNA
XM_
    mRNA (Computed)
NP_
    Protein
XP_
    Protein (Computed)
NR_
    RNA
XR_
    RNA(Computed)

Domain
The Conserved Domain Database (CDD) is a collection of multiple sequence alignments that represent functional domains conserved across evolution. Conserved Domains (CDs) are recurring polypeptide chains or modules which have distinct evolutionary origin and function.

PROW
Protein Reviews On the Web (PROW) contains authoritative and peer-reviewed short summaries on proteins and protein families.


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