University of Southern California

NCBI Structure Databases

Domains
NCBI's Conserved Domain Database (CDD) is a collection of multiple sequence alignments that represent functional domains conserved across evolution. Conserved Domains (CDs) are recurring polypeptide chains or modules which have distinct evolutionary origin and function.

Structure (MMDB)
The Molecular Modeling Database (MMDB) contains 3D macromolecular structures retrieved from the Protein Data Bank (PDB) database. MMDB contains over 28,000 structures which are determined by experimental methods, primarily X-ray crystallography and Nuclear Magnetic Resonance (NMR) spectroscopy. Theoretical models are not included.

3D Domains
The 3D Domains are annotations on individual Molecular Modeling Database (MMDB) structures that define compact structural domains contained within them.


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