University of Southern California

Nucleic Acid Structure Analysis

MFOLD
MFOLD is a widely used nucleic acid secondary structure prediction program developed by Dr. Michael Zuker using thermodynamic methods. Dr. Zuker provides the web interface for both RNA-folding and DNA-folding. The source codes and executables can be downloaded.

Hybrid
Hybrid is a a program developed by Dr. Zuker to calculate the hybridization of two different stands of DNA or RNA. The source codes and executables can be downloaded.

RNABase
RNABase is a database for RNA Structure.

NDB
The Nucleic Acid Database Project (NDB) is a repository of three-dimensional structural information about nucleic acids

SCOR
Structural Classification of RNA Database (SCOR) is a database designed to provide a comprehensive perspective and understanding of RNA motif structure, function, tertiary interactions and their relationships.

World Index of Molecular Visualization Resources
World Index of Molecular Visualization Resources is a repository of links to tutorials, demos, structural databases, galleries of images and visualization programs.

Mc-Sym
Mc-Sym is a software program that builds RNA 3-D structures using coordinates and relations between residues extracted from X-ray crystallography and NMR found in the RCSB Protein Data Bank and the Rutgers Nucleic Acid Database and from theoretical models.

Vienna RNA Package
Vienna RNA Package is a programming package to predict RNA secondary structure through energy minimization.

COVE, RNABOB, and PKNOTs
COVE, RNABOB, and PKNOTs are programs developed by Dr. Sean Eddy. COVE is for RNA structure analysis using covariance models; RNABOB is for pattern searching for RNA secondary structures; and PKNOTs is for RNA pseudoknot prediction.

RNAdraw
RNAdraw is an integrated program for RNA secondary structure calculation and analysis.

SStructView
SStructView is a Java applet for RNA secondary structure.


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