University of Southern California

USC Neuroscience

Mark S. Humayun

Professor of Biomedical Engineering and Cell and Neurobiology
Associate Director of Research at the Doheny Retina Institute at USC

Research Topics

  1. Electrical stimulation of the retina
  2. Retinal prosthesis
  3. Retinal disease
  4. Instrumentation for vitreoretinal surgery

Research Overview

Contact Information

Web Sites:
Department of Energy Artificial Retina
Mailing Address:
Doheny Eye Institute
1355 San Pablo Street, DVRC 119
Los Angeles, CA 90033
Office Phone:
(323) 442-6523
(323) 442-6755


  • Duke University Medical School, M.D.
  • University of North Carolina, Biomedical Engineering, PhD.

Research Images

Selected Publications

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Ameri H, Ratanapakorn T, Rao NA, Chader GJ, Humayun MS. (2008)  Natural course of experimental retinal vein occlusion in rabbit; arterial occlusion following venous photothrombosis. Graefes Arch Clin Exp Ophthalmol. (In press). -PubMed

Lo R, Li PY, Saati S, Agrawal R, Humayun MS, Meng E. (2008) A refillable microfabricated drug delivery device for treatment of ocular diseases. Lab Chip. 2008 Jul;8(7):1027-1030. -PubMed

de Balthasar C, Patel S, Roy A, Freda R, Greenwald S, Horsager A, Mahadevappa M, Yanai D, McMahon MJ, Humayun MS, Greenberg RJ, Weiland JD, Fine I. (2008)  Factors affecting perceptual thresholds in epiretinal prostheses. Invest Ophthalmol Vis Sci. 49(6):2303-2314. -PubMed

Lim TH, Humayun MS, Yoon YH, Kwon YH, Kim JG. (2008) The efficacy of retrobulbar block anesthesia only in pars plana vitrectomy and transconjunctival sutureless vitrectomy. Ophthalmic Surg Lasers Imaging. 39(3):191-195. -PubMed

Ahuja AK, Behrend MR, Whalen JJ, Humayun MS, Weiland JD. (2008) The dependence of spectral impedance on disc microelectrode radius. IEEE Trans Biomed Eng. 55(4):1457-1460. -PubMed

Ameri H, Kim JG, Ratanapakorn T, Chader GJ, Humayun MS. (2008) Intravitreal and subretinal injection of tissue plasminogen activator (tPA) in the treatment of experimentally created retinal vein occlusion in rabbits. Retina. 28(2):350-355. -PubMed

Fang SY, Deboer CM, Humayun MS. (2008) Performance analysis of new-generation vitreous cutters. Graefes Arch Clin Exp Ophthalmol. 246(1):61-67. -PubMed

Ameri H, Chader GJ, Kim JG, Sadda SR, Rao NA, Humayun MS. (2007) The effects of intravitreous bevacizumab on retinal neovascular membrane and normal capillaries in rabbits. Invest Ophthalmol Vis Sci. 48(12):5708-5715. -PubMed

Huang CC, Zhou Q, Ameri H, Wu da W, Sun L, Wang SH, Humayun MS, Shung KK. (2007) Determining the acoustic properties of the lens using a high-frequency ultrasonic needle transducer. Ultrasound Med Biol. 33(12):1971-1977. -PubMed

Huang CC, Ameri H, Deboer C, Rowley AP, Xu X, Sun L, Wang SH, Humayun MS, Shung KK. (2007)  Evaluation of lens hardness in cataract surgery using high-frequency ultrasonic parameters in vitro. Ultrasound Med Biol. 33(10):1609-1616. -PubMed