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The following are examples of some of the graduate courses available to PIBBS students at USC. The course syllabi for some of the courses at the Keck School of Medicine have been compiled by Dr. Judy A. Garner and are listed here.

TitleAdvanced Neurosciences I
DescriptionMolecular, cellular systems, cognitive, and computational approaches to the study of neurobiology.
FacultyBaudry, Bottjer, Byerly, Liman, Mel, Selleck
Course #BISC 524 (4 units, Fall)

TitleAnimal Virology
DescriptionVirus structure and chemistry; virus-cell interactions; virus genetics and molecular biology; pathogenesis, immunology, and evolution of viral infections
FacultyOu, Lai, Kohn, Tahara, Comai
Course #MICB 542 (2 units, Spring, alternate years)

TitleBiochemical and Molecular Basis of Disease
DescriptionMolecular mechanisms of genetic and metabolic diseases
FacultyRoy-Burman, Goodman, Reichardt, McDonough, Stallcup, Haworth, Reddy, Comai, Dennert, Lai, DeClerck, Chuong, Epstein, Kohn
Course #INTD 555 (4 units, Spring, alternate years)

TitleBiochemistry
DescriptionPhysical-chemical basis of life processes: protein structure and enzyme function; synthesis and metabolism of carbohydrates, lipids, amino acids, and nucleotides.
FacultyDanenberg, DeClerck, Kalra, Markland, Stellwagen, Comai
Course #INTD 571 (4 units, Fall)

TitleCell Biology
DescriptionMembranes structure and function; growth, metabolism, and signal transduction; cytoskeleton structure and regulation; intracellular trafficking; influences of extracellular matrix and cell environment
FacultyMircheff, Farley, Fulle, Schonthal, Schauwecker, Hamm-Alvarez, Garner, Okamoto, Chuong, DeClerck, Wu, Chow, Tuan, Sung
Websitehttp://www-hsc.usc.edu/~jgarner/cellbio/INTD531.html
Course #INTD 531 (4 units, Fall)

TitleCellular and Molecular Basis of Animal Development
DescriptionProcesses of cell type specification, determination, and morphogenesis in metazoans from vertebrates to insects. Genetic, paragenetic, and molecular biological approaches to developmental processes.
FacultyMaxson, Chuong, Snead, Chai, Shuler, Sucov
Course #BIOC 542 (4 units, Fall, alternate years)

TitleComputational Genome Analysis
DescriptionAn introduction to the computational side of molecular biology, emphasizing genome analysis. Basics of computational and statistical thinking within the context of biology. Organisms and their genomes; DNA computers; algorithms and methods for constructing restriction maps and physcial maps; comparison of DNA sequences; strategies and methods for large scale genome sequencing and sequence assembly; hybridization to DNA micro-arrays and analysis of data; tree-building analysis of DNA sequence as a tool for evolutionary biology; finding genes and signals in DNA; introduction to proteomics.
FacultyDeonier, Tavaré, Waterman
Course #BISC 478 (4 units)

TitleComputational Molecular Biology Lab
DescriptionPractical experience in computational molecular biology applications; statistical packages relevant to genomic analysis; retrieval and analysis of genomic data from databases.
FacultyTavaré
Course #MATH 577a (2 units)

TitleEpidemiology and Demographic Methods
DescriptionTerminology and uses of epidemiology and demography; sources and uses of population data; types of epidemiological studies; risk assessment; common sources of bias in population studies; principles of screening
FacultyAzen
Course #PM 512 (4 units, Spring)

TitleEukaryotic Molecular Genetics
DescriptionDNA and RNA structure and function; biochemistry and molecular biology of replication, transcription, RNA processing, translation; regulation of gene expression.
FacultyStellwagen, Haworth, Reddy, Lieber, Maxson, Laird, Johnson, Stallcup, Schonthal, Zandi, Laird-Offringa, Duncan
Course #INTD 561 (4 units, Spring)

TitleGenetic and Molecular Epidemiology
DescriptionGenetic principles; design and analysis of family trait and biomarker inheritance studies; relevant laboratory methods; estimation of likelihood; segregation and linkage analysis; biomarkers of exposure, susceptibility, and disease; susceptibility genes; association and linkage disequilibrium
FacultyIngles
Course #PM 533 (3 units)

TitleHuman Molecular Genetics
DescriptionBasic principles of human genetics, genetic disease, human genome project, and gene therapy.
FacultyReddy, Reichardt, Hacia, Hsieh, Coetzee, Lieber
Course #BIOC 543 (4 units, Fall, alternate years)

TitleMolecular Biology of Cancer
DescriptionTumor pathology, mechanisms of mutagenesis and carcinogenesis, chromosomal abnormalities, cell cycle and signaling, retroviruses, metastasis, angiogenesis, hormonal influences, cancer characteristics in a variety of specific organs, gene therapy, immunotherapy, animal models.
FacultyCoetzee, Dubeau, Ursin, Lieber, Goodman, Landolph, Pike, Lee, Maxson, Jones, Anderson, Weber, Press, Ross, Laird, Laird-Offringa, Weinberg, Shibata, Hsieh, Zandi
Course #INTD 504 (4 units, Spring, alternate years)

TitlePharmacogenomics
DescriptionUse of micro-array analysis, bioinformatics, and proteomics in pharmacology
FacultyNeamati
Course #PSCI 599 (2 units, Fall, alternate years)

TitlePrinciples of Biostatistics
DescriptionNature, scope, and terminology of biostatistics; appropriate uses and common misuses of health statistics; application of selected statistical procedures; introduction to statistical software packages
FacultyAzen
Course #PM 510L (4 units, Fall or Spring)

TitleProkaryotic & Eukaryotic Molecular Biology
DescriptionCurrent molecular, genetic, and biophysical methods for studying replication, recombination, mutagenesis, and repair. Fundamentals of transcription and regulation of gene expression. Recent applications of genetic engineering and genome analysis.
FacultyArnheim, Petruska, Suskind, Aparicio, Finkel, Tower, Goodman
Course #BISC 502a & b (a: 4 units, Fall; b: 4 units, Spring)

TitleSignal Transduction in Pharmacology and Toxicology
DescriptionReceptor theory and classification; basic pharmacology; second messengers; kinases and phosphatases; steroid and nuclear receptors; oxidative stress; cell cycle and apoptosis.
FacultySevanian, Brinton, Fulle, Torres, Schonthal, Duncan, Stallcup
Course #MPTX 500 (4 units, Fall)

TitleStatistical Methods in Human Genetics
DescriptionIntroduction to statistical methods used in analysis of human genetic data. Basic population genetics, linkage analysis, and association analysis. Methods and strategy of positional cloning of genes predisposing for complex diseases. Students will be introduced to basic theory, methods, and concepts and will gain practical experience through analysis of real data. The course will draw heavily on topical literature covering statistical methods and positional cloning.
FacultyWatanabe
Course #PM 535 (4 units, Spring)

TitleStatistics and Probability
DescriptionProbability spaces, discrete and continuous distributions, functions, sequences of random variables, special probability; principles for testing hypotheses and estimation, small sample distributions, correlation and regression, nonparametric methods, statistical decision theory
FacultyTavaré
Course #MATH 407 & 408 (407: 3 units, Fall; 408: 3 units, Spring)

TitleSystems Physiology and Disease
DescriptionPrinciples of feedback and homeostasis; emphasis on the cellular and integrative functions of the endocrine, nervous, sensory, cardiovascular, respiratory, gastrointestinal, kidney, and reproductive systems.
FacultyMcDonough, Farley, Meiselman, Keens, Mircheff, Peti-Peterdi, Snow, Yu, Wang, Schroeder, Hofman, Lubman, Brown, JC Wood, Nadim, Madkour
Course #INTD 562 (4 units, Fall)

Last updated: Tue May 13 00:22:12 2008

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