Brian E. Henderson Professor and Dean Preventive Medicine (Division of Epidemiology) Keck School of Medicine

Education:
BA 1958 English- University of California at Berkley, California
MD 1962 Medicine- University of Chicago, Illinois

Started at USC: 1970

Research Topics: Cancer Prevention/Epidemiology

Research Description

Dr. Henderson's major research interests are the epidemiology and genetics of the hormone related cancers of the breast, prostate, ovary, testes and endometrium. He is the Co-PI with Dr. Laurence Kolonel in Hawaii of a large Multi-ethnic long-term cohort study.

Selected Publications

Park SY, Murphy SP, Wilkens LR, Henderson BE, Kolonel LN. - Legume and isoflavone intake and prostate cancer risk: The Multiethnic Cohort Study. - Int J Cancer [ 2008 ] Jun 2;123(4):927-932 . PubMed

Edwards QT, Li AX, Pike MC, Kolonel LN, Ursin G, Henderson BE, McKean-Cowdin R. - Ethnic differences in the use of regular mammography: the multiethnic cohort. - Breast Cancer Res Treat [ 2008 ] May 21; . PubMed

Pearce CL, Van Den Berg DJ, Makridakis N, Reichardt JK, Ross RK, Pike MC, Kolonel LN, Henderson BE. - No Association between the SRD5A2 Gene A49T Missense Variant and Prostate Cancer Risk: Lessons Learned. - Hum Mol Genet [ 2008 ] May 10; . PubMed

Stacey SN, Manolescu A, Sulem P, Thorlacius S, Gudjonsson SA, Jonsson GF, Jakobsdottir M, Bergthorsson JT, Gudmundsson J, Aben KK, Strobbe LJ, Swinkels DW, van Engelenburg KC, Henderson BE, Kolonel LN, Le Marchand L, Millastre E, Andres R, Saez B, Lambea J, Godino J, Polo E, Tres A, Picelli S, Rantala J, Margolin S, Jonsson T, Sigurdsson H, Jonsdottir T, Hrafnkelsson J, Johannsson J, Sveinsson T, Myrdal G, Grimsson HN, Sveinsdottir SG, Alexiusdottir K, Saemundsdottir J, Sigurdsson A, Kostic J, Gudmundsson L, Kristjansson K, Masson G, Fackenthal JD, Adebamowo C, Ogundiran T, Olopade OI, Haiman CA, Lindblom A, Mayordomo JI, Kiemeney LA, Gulcher JR, Rafnar T, Thorsteinsdottir U, Johannsson OT, Kong A, Stefansson K. - Common variants on chromosome 5p12 confer susceptibility to estrogen receptor-positive breast cancer. - Nat Genet [ 2008 ] Jun;40(6):703-6 . PubMed

Garcia-Closas M, Hall P, Nevanlinna H, Pooley K, Morrison J, Richesson DA, Bojesen SE, Nordestgaard BG, Axelsson CK, Arias JI, Milne RL, Ribas G, González-Neira A, Benítez J, Zamora P, Brauch H, Justenhoven C, Hamann U, Ko YD, Bruening T, Haas S, Dork T, Schurmann P, Hillemanns P, Bogdanova N, Bremer M, Karstens JH, Fagerholm R, Aaltonen K, Aittomäki K, von Smitten K, Blomqvist C, Mannermaa A, Uusitupa M, Eskelinen M, Tengstrom M, Kosma VM, Kataja V, Chenevix-Trench G, Spurdle AB, Beesley J, Chen X, Australian Ovarian Cancer Management Group, Kathleen Cuningham Foundation Consortium For Research Into Familial Breast Cancer, Devilee P, van Asperen CJ, Jacobi CE, Tollenaar RA, Huijts PE, Klijn JG, Chang-Claude J, Kropp S, Slanger T, Flesch-Janys D, Mutschelknauss E, Salazar R, Wang-Gohrke S, Couch F, Goode EL, Olson JE, Vachon C, Fredericksen ZS, Giles GG, Baglietto L, Severi G, Hopper JL, English DR, Southey MC, Haiman CA, Henderson BE, Kolonel LN, Le Marchand L, Stram DO, Hunter DJ, Hankinson SE, Cox DG, Tamimi R, Kraft P, Sherman ME, Chanock SJ, Lissowska J, Brinton LA, Peplonska B, Klijn JG, Hooning MJ, Meijers-Heijboer H, Collee JM, van den Ouweland A, Uitterlinden AG, Liu J, Lin LY, Yuqing L, Humphreys K, Czene K, Cox A, Balasubramanian SP, Cross SS, Reed MW, Blows F, Driver K, Dunning A, Tyrer J, Ponder BA, Sangrajrang S, Brennan P, McKay J, Odefrey F, Gabrieau V, Sigurdson A, Doody M, Struewing JP, Alexander B, Easton DF, Pharoah PD. - Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics. - PLoS Genet [ 2008 ] Apr 25;4(4):e1000054 . PubMed

Albright CL, Steffen AD, Wilkens LR, Henderson BE, Kolonel LN. - The prevalence of obesity in ethnic admixture adults. - Obesity (Silver Spring) [ 2008 ] May;16(5):1138-43 . PubMed

Haiman CA, Garcia RR, Kolonel LN, Henderson BE, Wu AH, Le Marchand L. - A promoter polymorphism in the CASP8 gene is not associated with cancer risk. - Nat Genet [ 2008 ] Mar;40(3):259-60; author reply 260-1 . PubMed

Lee E, McKean-Cowdin R, Ma H, Chen Z, Van Den Berg D, Henderson BE, Bernstein L, Ursin G. - Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients. - Breast Cancer Res [ 2008 ] 10(1):R19 . PubMed

Haiman CA, Hsu C, de Bakker PI, Frasco M, Sheng X, Van Den Berg D, Casagrande JT, Kolonel LN, Le Marchand L, Hankinson SE, Han J, Dunning AM, Pooley KA, Freedman ML, Hunter DJ, Wu AH, Stram DO, Henderson BE. - Comprehensive association testing of common genetic variation in DNA repair pathway genes in relationship with breast cancer risk in multiple populations. - Hum Mol Genet [ 2008 ] Mar 15;17(6):825-34 . PubMed

Cox DG, Bretsky P, Kraft P, Pharoah P, Albanes D, Altshuler D, Amiano P, Berglund G, Boeing H, Buring J, Burtt N, Calle EE, Canzian F, Chanock S, Clavel-Chapelon F, Colditz GA, Feigelson HS, Haiman CA, Hankinson SE, Hirschhorn J, Henderson BE, Hoover R, Hunter DJ, Kaaks R, Kolonel L, LeMarchand L, Lund E, Palli D, Peeters PH, Pike MC, Riboli E, Stram DO, Thun M, Tjonneland A, Travis RC, Trichopoulos D, Yeager M. - Haplotypes of the estrogen receptor beta gene and breast cancer risk. - Int J Cancer [ 2008 ] Jan 15;122(2):387-92 . PubMed