USC logo
University of Southern California
PIBBS Online ApplicationPIBBS CalendarContact PIBBSPIBBS Faculty DirectoryPIBBS Site Index
PIBBS Home PageFaculty ResearchFaculty DirectoryPhD ProgramsOnline Application
Research Centers and Institutes Faculty Research Support Seminars and Symposia PIBBS Faculty in the News


Clay Wang

Assistant Professor

Pharmaceutical Sciences
School of Pharmacy
Photo Not Available

Send E-mail to:   clayw@usc.edu 
Telephone: 323-442-1670Fax: 323-442-1365
Office: PSC 704Mail Code: 9121 HSC

Education:
AB 1996 Chemistry- Harvard University
PhD 2001 Chemistry- California Institute of Technology, Pasadena

Postdoctoral Research Fellowship:
2001-2003 Stanford University, California

Started at USC: 2003

Research Topics: Gene Regulation/Transcription, Drug Design, Delivery, DNA & RNA

Click here for:PubMed SearchNIH GrantsResearch KeywordsSearch USC for Professor Wang

See also:     All USC Research GrantsAll HSC Research Grants

USC News Story:   NIH Grant Goes to USC Pharmacy School

USC News Story:   USC School of Pharmacy faculty members join Pan-Pacific International conference

USC News Story:   USC Takes Part in Pan-Pacific Conference

USC News Story:   Pharmacy dean in spotlight at Asian conference

USC News Story:   Pete Vanderveen Establishes Ties in Asia

     See Also:      All PIBBS Faculty in the News

Research Description

-chemical approaches toward gene regulation

-bioengineering and biosynthesis of natural products

Wang Group Research Projects

1. Chemical approaches toward gene regulation

Elucidation of gene function is an important task in this post genome era. We are interested in designing chemical probes that would allow us to turn off gene expression. We would like our chemical probes to possess three features (1) generally applicable (2) externally controllable (3) orthogonally inducible. We hope to use our chemical probes to study cell cycle regulators that play critical roles in cancers.

2. Bioengineering of polyketide natural products

We are interested in understanding how nature synthesizes important anti cancer agents. Using molecular biology and chemistry, we hope to reengineer these biosynthetic pathways in order to create new anti tumor agents.


Selected Publications

Pfeifer BA, Wang CC, Walsh CT, Khosla C. - Biosynthesis of Yersiniabactin, a complex polyketide-nonribosomal peptide, using Escherichia coli as a heterologous host. - Appl Environ Microbiol [ 2003 ] Nov;69(11):6698-702 . PubMed

Watanabe K, Wang CC, Boddy CN, Cane DE, Khosla C. - Understanding substrate specificity of polyketide synthase modules by generating hybrid multimodular synthases. - J Biol Chem [ 2003 ] Oct 24;278(43):42020-6 . PubMed


NCBI Disclaimers and copyright notice
Last updated: Mon Jun 30 16:26:33 2008

Return to   PIBBS home page  |  Research Topics page
  For more information contact the PIBBS Program

University of Southern California
1975 Zonal Avenue KAM-B16
Los Angeles, California 90089-9031
323-442-1609 (voice) / 323-442-1199 (fax)
E-mail: pibbs@usc.edu
 
 
© 1998-2008 The University of Southern California
 ..