Research Funding Opportunites

Research Funding Opportunites - Current Notices
Office of Scientific Affairs, Keck School of Medicine
Francis S. Markland Jr, PhD, Associate Dean
All information is provided by the sponsoring organization. For more information, please check with the contact person indicated for each notice or visit the website (where available). To submit a new funding notice for this page, please click here: Submission Form. Click here for: Previous Notices
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Special Document Prepared for USC: NIH and CDC Funding Opportunities - May 2006

Table of Contents
	Due date	Annual funding	Yrs support	Title of notice
1	None given		None given	Five NIH institutes have issued a joint announcement for small business grants	Print
2	May 02, 2009	275 K	2 years	NIH - HIV Proteins and Their Cellular Binding Partners	Print
3	Dec 09, 2007	250 K	5 years	Quick-Trials for Novel Cancer Therapies: Exploratory Grants (R21) - NIH	Print
4	Sep 01, 2009		5 years	Ruth L. Kirschstein National Research Service Award (NRSA)	Print
5	Sep 01, 2009		None given	The Role of Nuclear Receptors in Tissue and Organismal Aging (R01)	Print
6	None given		5 years	Mentored Clinical Scientist Development Award	Print
7	None given		None given	National Institutes of Health Adopts Careful Approaches	Print
8	None given		None given	Department of the Army Research Instrumentation Grant	Print
9	Jun 05, 2007		5 years	National Cancer Institute/NIH/DHHS Stem Cells and Cancer (R01)	Print
10	Jun 16, 2007		2 years	Stem Cell Differentiation for Cell-Based Therapies for Heart, Lung, and Blood, and Aging Diseases (R21)	Print
11	None given		None given	The Department of Defense Prostate Cancer Research Program received $80 million in Congressional appropriations for 2007	Print
12	None given	275 K	2 years	National Cancer Institute/NIH/DHHS Stem Cell Funding	Print
13	None given		None given	2008 Howard Hughes Investigator Competition	Print
14	None given		None given	NIH Announcement	Print
15	None given		None given	Pilot Study to Shorten the Review Cycle for New Investigator R01 Applications	Print
16	None given		None given	GrantsNet 2.0 Funding Opportunity Web Site	Print

Title of notice	Five NIH institutes have issued a joint announcement for small business grants
Notice type:	Request for proposals
Grant type:	Research
Research type:	Basic science and Clinical
Funding type:	Federal
Years of support:	None given
Due date:	None given
Description:	Printer-friendly
	Bioengineering Approaches to Energy Balance and Obesity Five NIH institutes, the National Heart, Lung, and Blood Institute, National Institute of Biomedical Imaging and Bioengineering, National Institute of Diabetes and Digestive and Kidney Diseases, National Cancer Institute, and National Institute on Aging, have issued a joint announcement for small business grants. Projects are sought that will develop and validate new and innovative bioengineering technology to address clinical problems related to energy balance, intake, and expenditure. Novel sensors, devices, imaging, and other approaches are expected to be developed and evaluated by collaborating engineers, physical scientists, and scientists from other disciplines with expertise in obesity and nutrition. • Small business technology transfer (R41/R42) and innovation (R43/R44) mechanisms Further details on these programs can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06-056.html and http://grants.nih.gov/grants/guide/pa-files/PA-06-055.html. (Note: An overview of NIH small business programs was presented in the November 11, 2005 Lewis-Burke Associates document entitled “University-Small Business Collaborations Viewed through the Lens of National Institutes of Health Research Opportunities”.) Date submitted: Tue, 03 Jan 2006 15:13:36 -0800 (PST)
Website:	http://grants.nih.gov/grants/guide/pa-files/PA-06-056.html and grants.nih.gov/grants/guide/pa-files/PA-06-055.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Tue, 03 Jan 2006 15:13:36 -0800 (PST)

Title of notice	NIH - HIV Proteins and Their Cellular Binding Partners
Notice type:	Request for proposals
Grant type:	Research
Research type:	Basic science and Clinical
Funding type:	Federal
Annual funding:	$ 275,000 per year
Years of support:	2 years
Due date:	May 02, 2009
Description:	Printer-friendly
	Program Number: 87995 Title: HIV Proteins and Their Cellular Binding Partners (R21/R33) Sponsor: National Institute of Allergy and Infectious Diseases/NIH/DHHS SYNOPSIS: The sponsor offers support for collaborations between biochemists and structural biologists to define the interactions of HIV proteins with their host-cell partners towards determining the three dimensional structure of these complexes. The goal is to gain an in-depth understanding of HIV protein-containing complexes throughout the virus life cycle. A better understanding of these interactions will lead to new avenues for therapeutic interventions in HIV disease. This program will use the NIH Phased Innovation Award (R21/R33) mechanism. Deadline(s): 10/01/2006 02/01/2007 06/01/2007 10/01/2007 02/01/2008 06/01/2008 10/01/2008 02/01/2009 09/01/2006 01/02/2007 05/01/2007 09/01/2007 01/02/2008 05/01/2008 09/01/2008 01/02/2009 05/01/2009 Established Date: 05/05/2006 Follow-Up Date: 03/01/2007 Review Date: 05/05/2006 Contact: Diana Finzi, Ph.D. Address: Division of AIDS Room 4219, MSC 7628 6700B Rockledge Drive Bethesda, MD 20892-7628 U.S.A. E-mail: dfinzi@niaid.nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PA-06-388.html Tel: 301-451-2598 Fax: 301-402-3211 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE Applications may be submitted to Grants.gov in response to this announcement on or after August 1, 2006. The deadlines for receipt of standard applications under this announcement are: February 1, June 1, and October 1 annually. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on May 2, 2009. Award Type(s): Demonstration/Evaluation Research Grants/R & D Collaborative Project Citizenship/Country of Applying Institution: Any/No Restrictions Locations Tenable: Any/No Restrictions Appl Type(s): Colleges/Universities For-Profit Hospital Indian Tribes/Governing Orgs. Laboratory Non-Profit Organizations--Community/Soc. Serv. Organizations--Health/Medical Private Institution/Organization Public Institution Research Institutions/Organizations Researcher/Investigator School of Medicine State/Local Agencies Target Group(s): NONE Funding Limit: $0 SEEBELOW Duration: 5 YEAR(s) Indirect Costs: Unspecified Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999 OBJECTIVES: The program will support studies that are particularly innovative, novel, and possibly high risk/high impact, and that have potential to advance understanding of the interactions of HIV proteins with cognate cellular binding partners. The ultimate goal of this program is the structural determination of HIV proteins complexed with their cellular binding partners. A critical first step in structural analysis of a complex is the investigation of the biology, biochemistry and biophysics of the protein: protein interaction. All areas of investigation contributing to understanding the interactions of HIV with cellular proteins are welcome. These may include but are not limited to studies using confocal microscopy, calorimetry, fluorescence resonance energy transfer, electron microscopy, cryoelectron tomography, nuclear magnetic resonance (NMR), x-ray tomography X-ray crystallography, and/or computational biology. Combinations of these methods and collaborative projects are strongly encouraged. ELIGIBILITY Eligible applicants are: for-profit or non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; units of State and local governments; units of State and local Tribal government; eligible agencies of the Federal government; domestic or foreign institutions/organizations; and faith-based or community-based organizations. FUNDING This program will use the NIH Phased Innovation Award (R21/R33) mechanism. Applicants may request up to two years of support for the R21 feasibility phase limited to $275,000 direct costs over the two year award period. Budgetary support for the R33 phase will be limited to $250,000 per annum in direct costs. F&A costs requested by consortium participants are not included in the direct cost limitation. CFDA#s: 93.855, 93.856. Reference: NIH Guide, Week Ending May 5, 2006. (kww) Date submitted: Mon, 08 May 2006 11:05:39 -0700 (PDT)
Website:	http://grants1.nih.gov/grants/guide/pa-files/PA-06-388.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Mon, 08 May 2006 11:05:39 -0700 (PDT)

Title of notice	Quick-Trials for Novel Cancer Therapies: Exploratory Grants (R21) - NIH
Notice type:	Request for proposals
Grant type:	Research
Research type:	?
Funding type:	Federal
Annual funding:	$ 250,000 per year
Years of support:	5 years
Due date:	Dec 09, 2007
Description:	Printer-friendly
	Program Number: 53900 Title: Quick-Trials for Novel Cancer Therapies: Exploratory Grants (R21) Sponsor: National Cancer Institute/NIH/DHHS SYNOPSIS: The sponsor provides investigators with rapid access to support for pilot, Phase I, and Phase II cancer clinical trials as well as support for patient monitoring and laboratory studies lined to a cancer clinical trial. This PA will use the NIH exploratory/development R21 award mechanism. Deadline(s): 08/09/2006 12/09/2006 04/09/2007 08/09/2007 12/09/2007 Established Date: 02/01/2000 Follow-Up Date: 07/01/2007 Review Date: 06/09/2006 Contact: Dr. Roy Wu Address: Clinical Grants & Contracts Branch, Cancer Therapy Evaluation Program Division of Cancer Treatment and Diagnosis, Executive Plaza North, Rm. 7009 6130 Executive Boulevard, EPN Room 7009 Bethesda, MD 20892-7432 U.S.A. E-mail: wur@ctep.nci.nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PAR-06-451.html Tel: 301-496-8866 Fax: 301-480-4663 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE This program expires on December 10, 2007, unless reissued. Award Type(s): Collaborative Project Development-Program Research Grants/R & D Demonstration/Evaluation Citizenship/Country of Applying Institution: Any/No Restrictions Locations Tenable: Any/No Restrictions Appl Type(s): Colleges/Universities For-Profit Hospital Laboratory Non-Profit Organizations--Health/Medical Public Institution Private Institution/Organization Researcher/Investigator Research Institutions/Organizations School of Medicine State/Local Agencies Organizations--Community/Soc. Serv. Indian Tribes/Governing Orgs. Target Group(s): NONE Funding Limit: $500,000 MAXIMUM Duration: 2 YEAR(s) Indirect Costs: Unspecified Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999 OBJECTIVES: The focus of this QUICK-TRIAL PA is on translational research in new agent development to ensure the timely exploitation of new cancer therapeutic approaches including the development of new cancer prevention agents. New clinical therapeutic trials may employ drugs/agents, biologics, radiation, heat, or surgery used as single agents/modalities or in combination for the treatment of early and advanced disease. In addition, clinical trials of therapies for cancer treatment, including but not limited to herbal therapies, dietary supplements, bioactive food components, or unconventional pharmacological and biological interventions (e.g. antineoplastons, Coley's toxin, enzyme therapies, etc.) will be considered. Another relevant area of investigation is the use of anatomical and molecular image guidance for targeted treatment with ablative techniques or delivery of chemotherapeutic agents. This PA will continue to support scientific, technological, clinical and logistical needs in novel cancer therapy development. ELIGIBILITY Eligible applicants are: for-profit or non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; units of State and local governments; units of State and local Tribal government; eligible agencies of the Federal government; domestic or foreign institutions/organizations; and faith-based or community-based organizations. FUNDING This program will use the NIH exploratory/developmental grant (R21) award mechanism. Applications submitted in response to this announcement must be submitted electronically through Grants.gov, using the SF424 Research and Related (R&R) forms and SF424 (R&R) Application Guide. The total project period for an application submitted in response to this funding opportunity may not exceed two years. Direct costs are limited to $500,000 over an R21 two-year period, with no more than $250,000 in direct costs allowed in any single year. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. F&A costs requested by consortium participants are not included in the direct cost limitation. Date submitted: Mon, 26 Jun 2006 13:09:02 -0700 (PDT)
Website:	http://grants1.nih.gov/grants/guide/pa-files/PAR-06-451.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Mon, 26 Jun 2006 13:09:02 -0700 (PDT)

Title of notice	Ruth L. Kirschstein National Research Service Award (NRSA)
Notice type:	Request for proposals
Grant type:	?
Research type:	?
Funding type:	Federal
Years of support:	5 years
Due date:	Sep 01, 2009
Description:	Printer-friendly
	Program Number: 03162 Title: Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32) Sponsor: National Institute on Aging/NIH/DHHS SYNOPSIS: The sponsor awards National Research Service Award (NRSA) Institutional Training Grants (T32) to eligible institutions as the primary means of supporting graduate and postdoctoral research training to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation’s biomedical, behavioral and clinical research agenda. The primary objective is to prepare qualified individuals for careers that have a significant impact on the health-related research needs of the Nation. This program will use the the Ruth L. Kirschstein National Research Service Award (NRSA) Institutional Research Training Grants (T32). Deadline(s): 09/10/2006 01/10/2007 05/10/2007 09/10/2007 01/10/2008 05/10/2008 09/10/2008 01/10/2009 05/10/2009 09/01/2006 01/02/2007 05/01/2007 09/01/2007 01/02/2008 05/01/2008 09/01/2008 01/02/2009 05/01/2009 09/01/2009 Established Date: 03/12/1985 Follow-Up Date: 03/01/2007 Review Date: 06/19/2006 Contact: Michael-David ARR Kerns, MBA, MS, PhD Address: 7201 Wisconsin Ave Suite 2C-218 Bethesda, MD 20892 U.S.A. E-mail: kernsmd@mail.nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PA-06-468.html Tel: 301-402-7713 Fax: 301-402-2945 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE The deadline for receipt of standard applications under this announcement are: January 10, May 10, and September 10 annually. Please note that some participating NIH Institutes and Centers do not accept T32 applications for all three receipt dates. Therefore, applicants are strongly encouraged to refer the the NIH T32 website (http://grants.nih.gov/grants/guide/contacts/pa-06-468_contacts.htm) associated with this funding opportunity announcement to determine IC specific submission dates. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on September 2, 2009. Award Type(s): Development-Program Research Grants/R & D Training/Professional Development Citizenship/Country of Applying Institution: Any/No Restrictions U.S. Non-Citizen National U.S. Permanent Resident U.S.A. Citizenship (including U.S. Territories) Locations Tenable: U.S.A. Institution (including U.S. Territories) Appl Type(s): Non-Profit Public Institution Postdoctoral Physician/Medical Professional Private Institution/Organization Graduate Student Colleges/Universities Doctoral-Midcareer/Senior Invst. Hospital Laboratory Target Group(s): NONE Funding Limit: $0 SEEBELOW Duration: 5 YEAR(s) Indirect Costs: Yes Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999 OBJECTIVES: The purpose of the NRSA research training program is to help ensure that a diverse and highly trained workforce is available to assume leadership roles related to the Nation’s biomedical and behavioral research agenda. Training activities can be in basic biomedical or clinical sciences, in behavioral or social sciences, in health services research, or in any other discipline relevant to the NIH mission. Research training programs are designed to allow the Training Program Director (TPD) to select the trainees and develop a curriculum of study and research experiences necessary to provide high quality research training. Each NIH Institute and Center has a unique scientific purview and different program goals and initiatives that evolve over time. It is therefore critical that all applicants consult with the scientific/research contact at the relevant NIH Institute or Center for current information about program priorities and policies before preparing an application (see http://grants.nih.gov/grants/guide/contacts/pa-06-468_contacts.htm).</ p> ELIGIBILITY Eligible applicants are: non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; and domestic institutions/organizations. At the time of appointment to the training program, individuals selected for research training supported by NRSA institutional training grants must be citizens or non-citizen nationals of the United States, or must have been lawfully admitted to the United States for permanent residence. Predoctoral trainees must have received a baccalaureate degree by the beginning date of their NRSA appointment, must be training at the post-baccalaureate level, and be enrolled in a program leading to a Ph.D. in science or in an equivalent research doctoral degree program. Health-professional students, graduate students in the quantitative sciences, or individuals in postgraduate clinical training who wish to interrupt their studies for a year or more to engage in full-time research training before competing their formal training programs are also eligible. Postdoctoral trainees must have received, as of the beginning date of the NRSA appointment, a Ph.D., M.D., D.D.S., or comparable doctoral degree from an accredited domestic or foreign institution. Eligible doctoral degrees include, but are not limited to, the following: D.M.D., D.C., D.O., D.V.M., O.D., D.P.M., Sc.D., Eng.D., Dr. P.H., D.N.Sc., Pharm.D., N.D. (Doctor of Naturopathy), D.S.W., Psy.D, as well as a doctoral degree in nursing research or practice. A Kirschstein NRSA-Institutional Research training application may include a request for short-term positions reserved specifically to provide full-time health-related research training experiences during the summer or other “off-quarter” period. Such positions are limited to medical students, dental students, students in other health-professional programs, and graduate students in the physical or quantitative sciences. To be eligible for short-term predoctoral research training positions, students must be enrolled and in good standing and must have completed at least one quarter in a program leading to a clinical doctorate or a masters or doctorate in a quantitative science such as physics, mathematics, or engineering prior to participating in the program. FUNDING Institutional NRSA research training grants (T32) may be made for periods up to five years. Trainee appointments are normally made in twelve-month increments. Short -term positions can support individuals for a period at least eight, but no more than twelve weeks in a grant year. No trainee may be appointed for less than nine months during the initial period of appointment, except with prior approval. No individual trainee may receive more than five years of aggregate NRSA support at the predoctoral level or three years of support at the postdoctoral level, including any combination of support from institutional training grants and individual fellowship awards. Any extensions require approval. A stipend is provided as a subsistence allowance to help trainees defray living expenses during the research training experience. For postdoctoral trainees the appropriate stipend level is based on the number of full years of relevant postdoctoral experience at the time of appointment. The NIH will offset the combined cost of tuition, fees, and health insurance (either self-only or family as appropriate) at the following rate: one hundred percent of all costs up to $3,000 and sixty percent of costs above $3,000. Trainee travel, including attendance at scientific meetings that the institution determines to be necessary to the individual's research training, is an allowable trainee expense. In addition, support for travel to a research training experience away from the institution may be permitted. The applicant institution may request the NIH standard NRSA Training Related Expenses (FY 2006, $2,200 annually for each predoctoral trainee and $3,850 annually for each postdoctoral trainee) to help defray other research training expenses, such as staff salaries, consultant costs, equipment, research supplies, and faculty/staff travel directly related to the research training program. Funding for short-term training is prorated, based on the allowed annual amounts for stipends and training related expenses. A facilities and administrative allowance (indirect cost allowance) based on eight percent of total allowable direct costs (this excludes amounts for tuition, fees, health insurance, and equipment) may be requested. Applications from state and local government agencies may request full indirect cost reimbursement. The grantee institution is allowed to provide funds to an individual in addition to the stipends paid by the NIH. Supplementation or additional support to offset the cost of living may be provided by the grantee institution. An institution may provide additional funds to a trainee in the form of compensation (as salary and/or tuition remission) for services such as teaching or serving as a research assistant. Date submitted: Mon, 26 Jun 2006 14:02:13 -0700 (PDT)
Website:	http://grants1.nih.gov/grants/guide/pa-files/PA-06-468.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Mon, 26 Jun 2006 14:02:13 -0700 (PDT)

Title of notice	The Role of Nuclear Receptors in Tissue and Organismal Aging (R01)
Notice type:	Request for proposals
Grant type:	Research
Research type:	Basic science and Clinical
Funding type:	Federal
Years of support:	None given
Due date:	Sep 01, 2009
Description:	Printer-friendly
	Program Number: 88701 Title: The Role of Nuclear Receptors in Tissue and Organismal Aging (R01) Sponsor: National Institute on Aging/NIH/DHHS SYNOPSIS: The sponsors offer support for research into underlying biologic mechanisms involving nuclear receptors, their co-regulators and intracellular signaling systems in the process of aging and the connections of the aging process with pathophysiology in middle- and old-age. This program will use the NIH R01 award mechanism. Deadline(s): 10/01/2006 02/01/2007 06/01/2007 10/01/2007 02/01/2008 06/01/2008 10/01/2008 02/01/2009 06/01/2009 09/01/2006 01/02/2007 05/01/2007 09/01/2007 01/02/2008 05/01/2008 09/01/2008 01/02/2009 05/01/2009 09/01/2009 Established Date: 06/19/2006 Follow-Up Date: 06/01/2007 Review Date: 06/19/2006 Contact: Jill Carrington, Ph.D. Address: Biology of Aging Program Gateway Building, Suite 2C231 7201 Wisconsin Avenue Bethesda, MD 20892-9205 U.S.A. E-mail: carringj@mail.nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PAS-06-467.html Tel: 301-496-6402 Fax: 301-402-0010 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE The deadlines for receipt of standard applications under this announcement are: February 1, June 1, and October 1 annually. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on September 2, 2009. Award Type(s): Research Grants/R & D Citizenship/Country of Applying Institution: Any/No Restrictions Locations Tenable: Any/No Restrictions Appl Type(s): Colleges/Universities For-Profit Hospital Laboratory Non-Profit Organizations--Health/Medical Private Institution/Organization Public Institution Research Institutions/Organizations Researcher/Investigator School of Medicine State/Local Agencies Target Group(s): NONE Funding Limit: $0 NOT PROV Duration: 0 Indirect Costs: Unspecified Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999 OBJECTIVES: The purpose of this initiative is to stimulate research into underlying biologic mechanisms involving NRs, their co-regulators and intracellular signaling systems, in the process of aging and the connection of the aging process with pathophysiology in middle- and old-age. The focus of the proposed research must be on processes of aging and/or age-related changes, i.e., research proposed in applications responding to this PA must have clear relevance to aging. Potential topic areas of interest to the NIA include, but are not limited to, the following: Age-changes in levels, sensitivity, and gene expression activation profiles of NRs and co-regulators, and their effects on processes of aging (e.g., age-changes in tissue function, inflammation, glucose and lipid metabolism, adipogenesis, muscle, and brain function) and connections with disease processes for diseases common in older individuals. Modification of lifespan in model organisms (e.g., the NR homologue DAF-12 in the insulin-IGF-like pathway in the nematode, and mammalian homologues) and the health-protecting, life-extending effects of caloric restriction or other life-span altering genetic mutations or transgenic models in mammalian organisms. Age-changes in steroid metabolism or in tissue sensitivity and/or response to exogenous sex steroid (or tissue-selective sex steroid receptor modulators) therapy in middle- and old-age. NIDDK is primarily interested in the underlying mechanisms of action of nuclear receptors, coregulators, as they may affect diseases/conditions often seen in an aging population, including type 2 diabetes and obesity. NCI is interested in understanding the role of nuclear hormone receptor superfamily as well as the orphan nuclear receptors, their coactivators/corepressors, in a number of human malignancies such as thyroid, lung, colon, pancreas, endometrium, ovary, breast and prostate. Areas of high cancer relevance include: understanding the role of the coregulators in regulating transcription by modifying chromatin and/or associated proteins, influencing epithelial-stromal interactions during cancer progression, contributing to hormone resistance, as well as in determining therapeutic response. NIEHS is primarily interested in: age changes in levels, sensitivity, and gene expression activation profiles of NRs and coregulators as stimulated by endogenous activators or environmental chemicals with endocrine activity; or tissue-selective sex steroid receptor modulators including environmental agents with hormonal activity. ELIGIBILITY Eligible applicants are: for-profit or non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; units of State and local governments; eligible agencies of the Federal government; and domestic or foreign institutions/organizations. FUNDING This program will use the NIH R01 award mechanism. Because the nature and scope of the proposed research will vary from application to application, it is anticipated that the size and duration of each award will also vary. F&A costs requested by consortium participants are not included in the direct cost limitation. Date submitted: Mon, 26 Jun 2006 14:08:15 -0700 (PDT)
Website:	http://grants1.nih.gov/grants/guide/pa-files/PAS-06-467.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Mon, 26 Jun 2006 14:08:15 -0700 (PDT)

Title of notice	Mentored Clinical Scientist Development Award
Notice type:	Announcement only
Grant type:	Research
Research type:	Basic science and Clinical
Funding type:	Federal
Years of support:	5 years
Due date:	None given
Description:	Printer-friendly
	Program Number: 52103 Title: Mentored Clinical Scientist Development Award (K08) Sponsor: National Institute on Aging/NIH/DHHS SYNOPSIS: The sponsors offer support for Mentored Clinical Scientist Research Career Development Awards, to support didactic study and mentored research for individuals with clinical doctoral degrees (e.g., M.D., D.D.S., D.M.D., D.O., D.C., O.D., N.D., D.V.M., Pharm.D., or Ph.D. in clinical disciplines). This award provides support and “protected time” for an intensive, supervised research career development experience in the fields of biomedical or behavioral research, including translational research. This program will use the Mentored Clinical Scientist Research Career Development Award (K08). Deadline(s): 10/01/2006 02/01/2007 06/01/2007 10/01/2007 02/01/2008 06/01/2008 10/01/2008 02/01/2009 06/01/2009 09/01/2006 01/02/2007 05/01/2007 09/01/2007 01/02/2008 05/01/2008 09/01/2008 01/02/2009 05/01/2009 09/01/2009 Established Date: 10/11/1999 Follow-Up Date: 09/01/2007 Review Date: 08/08/2006 Contact: Dr Robin A. Barr Address: Office of Extramural Activities Gateway Building, Room 2C218 7201 Wisconsin Avenue, MSC 9205 Bethesda, MD 20892-9205 U.S.A. E-mail: BarrR@mail.nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PA-06-512.html Tel: 301-496-9322 Fax: 301-402-2945 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE The deadlines for receipt of standard applications under this announcement are: February 1, June 1, and October 1 annually. The deadlines for receipt of AIDS-related applications are: January 2, May 1, and September 1 annually. This program will expire on September 2, 2009. Award Type(s): Research Grants/R & D Training/Professional Development Citizenship/Country of Applying Institution: U.S. Non-Citizen National U.S.A. Citizenship (including U.S. Territories) U.S. Permanent Resident Any/No Restrictions Locations Tenable: Any/No Restrictions U.S.A. Institution (including U.S. Territories) Appl Type(s): Colleges/Universities Public Institution Private Institution/Organization School of Dentistry School of Medicine School of Nursing Physician/Medical Professional Postdoctoral Young Investigator/Junior Faculty Nurse School of Allied Health School of Optometry School of Osteopathy School of Pharmacy School of Veterinary Medicine Target Group(s): NONE Funding Limit: $0 SEEBELOW Duration: 5 YEAR(s) Indirect Costs: Yes Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999 OBJECTIVES: The objective of the Mentored Clinical Scientist Research Career Development Award (K08) is to continue the long standing NIH support of didactic study and mentored research for individuals with clinical doctoral degrees (e.g., M.D., D.D.S., D.M.D., D.O., D.C., O.D., N.D., D.V.M., Pharm.D., or Ph.D. in clinical disciplines). This award provides support and “protected time” for an intensive, supervised research career development experience in the fields of biomedical or behavioral research, including translational research. For the purpose of this award, translational research is defined as application of basic research discoveries toward the diagnosis, management, and prevention of disease. The K08 award may be used by candidates with different levels of prior research training and at different stages in their career development. For example, a candidate with limited experience in a given field of research may use an award to support a career development experience that includes a designated period of didactic training followed by a period of closely supervised research experience. A candidate with previous research experience and training may not require extensive additional didactic preparation, and may use an award to support a career development experience that focuses on an intensive, supervised research experience. ELIGIBILITY Eligible applicants are: for-profit or non-profit organizations; public or private institutions, such as universities, colleges, hospitals, and laboratories; and domestic institutions/organizations. The applicant institution must have a strong, well-established record of research and career development activities and faculty qualified in biomedical, behavioral, or clinical research to serve as mentors. Only U.S. citizens or non-citizen nationals, or individuals lawfully admitted for permanent residence who possess an Alien Registration Receipt Card (I-151 or I-551), or some other verification of legal admission as a permanent resident prior to the time of award, are eligible for this award. Candidates for this award must have a clinical doctoral degree or its equivalent. Such degrees include but are not limited to the M.D., D.O., D.D.S., D.M.D., O.D., D.C., Pharm.D., N.D. (Doctor of Naturopathy). Individuals with the Ph.D. or other doctoral degree in clinical disciplines such as clinical psychology, nursing, clinical genetics, speech-language pathology, audiology or rehabilitation are also eligible. Candidates must be able to commit a minimum of seventy-five percent of full-time professional effort conducting research career development activities associated with this award. The remaining twenty-five percent effort can be divided among other research, clinical, and teaching activities only if these activities are consistent with the goals of the K08 Award, i.e., the candidate’s development into an independent investigator. At the time of award, the candidate must have a “full-time” appointment at the academic institution that is the applicant institution. FUNDING This program will use the Mentored Clinical Scientist Research Career Development Award (K08). Applicants may request 3 to 5 years of support. The actual duration of the award will depend upon the number of years of prior research experience and the need for additional experience to achieve independence, and the policy of the awarding Institute or Center (IC).Because the nature and scope of the proposed K08 award program will vary from application to application and the amounts provided by the participating ICs are not uniform, it is anticipated that the size and duration of each award will also vary. Facilities and Administrative costs will be reimbursed at eight percent of modified total direct costs. Awards will provide salary and research development support for candidates. Date submitted: Wed, 09 Aug 2006 15:05:47 -0700 (PDT)
Website:	http://grants1.nih.gov/grants/guide/pa-files/PA-06-512.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Wed, 09 Aug 2006 15:05:47 -0700 (PDT)

Title of notice	National Institutes of Health Adopts Careful Approaches
Notice type:	Announcement only
Grant type:	?
Research type:	?
Funding type:	Federal
Years of support:	None given
Due date:	None given
Description:	Printer-friendly
	Federal Biomedical Research in Transition: National Institutes of Health Adopts Careful Approaches in Context of Fiscal Realities for FY2006 and FY2007 The National Institutes of Health (NIH) is facing unprecedented challenges as it struggles to sustain the biomedical research enterprise with the needed new initiatives at a time of rapid discovery. Because NIH anticipates, at best, a flat funding level for FY2007, its fiscal prudence is evident in recently announced initiatives. Research programs are being reconfigured, with careful selection (or elimination) of funding mechanisms to assure maintenance of viability in critical areas. NIH Roadmap concepts and principles are becoming more integrated into individual institute solicitations that are synergistic with Roadmap-specific funding opportunities; institutes are increasingly collaborating with one another, with other federal agencies, and with the private sector. Because NIH is not expanding its portfolio of large ticket funding mechanisms (such as centers, program projects, and large resource grants), there is evidence that individual institutes are rethinking their funding strategies. For example, the National Institute of Neurological Disorders and Stroke announced in August that it will not accept new or amended core center grants (P30) and plans for future support are not certain (see http://grants.nih.gov/grants/guide/notice- files/NOT-NS-06-016.html). The National Eye Institute has reconfigured its support of clinical study planning grants (http://grants.nih.gov/grants/guide/notice-files/NOT-EY-06-005.html.) And, NIH has increased use of formal “Requests for Information” to assist its decision-making on both scientific directions and administrative processes; this document contains several examples. (The research community should take advantage of these excellent opportunities to provide advice to NIH.) Potential applicants are exhorted more than ever before to engage in “preapplication consultation” with grant portfolio managers prior to submission of grant applications. To stimulate new or needed areas of endeavor or to reinvigorate ongoing programs under current fiscal constraints, the prime strategy now appears to be coupled initiatives for support of research projects (R01), exploratory or developmental awards (R21), small grants (R03), and in some cases, small business awards (SBIR, STTR). This document provides a number of examples in that regard, particularly in the “Models, Materials, and Methods” and “Diabetes and Obesity” sections. The “Bioengineering” section provides examples in which multidisciplinary programs are being driven via the research project grant (R01) mechanism. NIH has also approached its static funding levels for training grants and fellowships by imposing more fiscal restraints. The “Pre- and Postdoctoral Training” section describes the latest fellowship reimbursement levels from NIH, as well as two new training programs for underrepresented populations and for behavioral scientists. As part of the government-wide initiative, NIH continues its transition to a fully electronic grants submission process. The use of the old PHS 398 application form is being phased out with the implementation of the SF-424 form in a mechanism-by-mechanism approach (as noted in a reminder notice issued by NIH in late June at http://grants.nih.gov/grants/guide/notice- files/NOT-OD-06-079.html). Some funding opportunities highlighted in this document provide examples of that ongoing implementation, as well as pilot implementation of the multiple principal investigator policy (http://grants2.nih.gov/grants/multi_pi/). Because the electronic approach for all grants processes has implications for the traditionally submitted appendix materials, NIH has asked for input by September 14, 2006 on the way that such materials should be used in the grant submission, review, and management process (notice at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-06-088.html). NOTE: While the submission date may have passed for a few of the funding opportunities described in this document, they are included as examples to illustrate some recent NIH approaches to disciplinary areas. TABLE OF CONTENTS I. Biological Pathways, Networks, and Systems A. Comparative Biology Elucidation of Environmental Pathways and Susceptibility 5 B. NHLBI Exploratory Program in Systems Biology 5 C. Using Metabolomics to Investigate Biological Pathways and Networks (Roadmap) 6 II. Models, Materials, and Methods A. Development of Nonmammalian Models and Related Biological Materials for Research 7 B. Assay Development for High Throughput Molecular Screening (Roadmap) 7 C. REQUEST FOR INFORMATION: Animal Model Resources Informatics 8 D. REQUEST FOR INFORMATION: Tools and Resources for Research in Neurodevelopment (Neuroscience Blueprint) 8 E. Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis 9 F. Technology Development for the Comprehensive Determination of Functional Elements in Eukaryotic Genomes 10 G. Development and Applications of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders 10 III. Bioengineering A. Enabling Technologies for Tissue Engineering and Regenerative Medicine 12 B. Bioengineering Research Partnerships 13 IV. Diabetes and Obesity A. Long-Term Weight Maintenance: Basic and Clinical Studies 14 B. Translational Research for the Prevention and Control of Diabetes and Obesity 14 C. Diet Composition and Energy Balance 15 D. Heterogeneity of Fat Depots: Underlying Basis and Association with Morbidity 16 E. Exploratory/Developmental Clinical Research Grants in Obesity 16 F. Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition 17 G. Diabetes Research Centers 17 H. Additional Major Affiliates needed to Join the Type I Diabetes TrialNet Clinical Network 18 I. School-based Interventions to Prevent Obesity 18 continued on next page V. Research Partnerships in Biodefense and Infectious Diseases A. Cooperative Research Partnerships into Therapeutics and Diagnostics for Biodefense 20 B. NIAID Partnerships with Public-Private Partnerships 20 VI. New Approaches to Clinical Studies A. NIAMS Clinical Trial Outcomes Instrument Development Grant Program 22 B. Innovative Therapies and Clinical Studies for Screenable Disorders 22 C. Specialized Programs of Research Excellence in Human Cancer for the Year 2007 23 D. Specialized Centers of Interdisciplinary Research on Sex and Gender Factors Affecting Women’s Health 24 VII. Economics, Health Services, and Integrative Treatment A. Neuroeconomics of Aging 25 B. Behavioral and Social Research on Disasters and Health 25 C. Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network 26 D. Behavioral and Integrative Treatment Development Program 27 E. Mental Health Issues in Communities (six solicitations) 27 VIII. Pre- and Postdoctoral Training A. New Policy for Funding of Tuition, Fees, and Health Insurance on Ruth L. Kirschstein National Research Service Awards 29 B. Predoctoral Training at the Interface of the Behavioral and Biomedical Sciences 30 C. Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research 30 A. Comparative Biology Elucidation of Environmental Pathways and Susceptibility Three of NIH’s institutes, the National Institute of Environmental Health Sciences, the National Institute on Alcohol Abuse and Alcoholism, and the National Heart, Lung and Blood Institute, indicate desire to support work on critical common pathways by which environmental stressors influence human health. Specifically, investigators are encouraged to consider two distinct approaches: (1) a genetically driven approach to define the gene-environment interactions contributing to pathophysiologic responses and individual susceptibility to disease and/or (2) a pathway and network-driven approach to define molecular mechanisms that mediate pathophysiological responses to toxins. Partnerships are encouraged to provide appropriate expertise in these highly multidisciplinary studies. • NEW • Research project (R01) grant mechanism • Up to $5.1 million is committed to fund 10 to 16 new grants in FY 2007. Within that, NIAAA plans to fund 1-2 grants with $500,000 allocated specifically to alcohol effects, while NHLBI commits $600,000 for up to 2 grants related to heart, lung, blood, or circadian timing research. (Note: the National Human Genome Research Institute may support applications deemed relevant to its mission, though it is not a formal cosponsor of the solicitation). Applicants may request project periods of up to four years and a budget of up to $350,000 direct cost per year. • Application receipt dates: September 18, 2006 (Letter of intent receipt dates: August 23, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-ES-06- 004.html. B. NHLBI Exploratory Program in Systems Biology The National Heart, Lung and Blood Institute invites researchers to apply systems biology approaches to innovative, high-risk, high-impact research on heart, lung, blood, and sleep physiology and pathophysiology. Projects should combine computational modeling and simulation approaches with experimental validation of model predictions. I. BIOLOGICAL PATHWAYS, NETWORKS, AND SYSTEMS • EXPANSION of ongoing program • Exploratory/development research grant phase II (R33) award mechanism • Up to $2.7 million in FY2007 and FY2008 to fund three new cluster grants each year is allocated. Applications must be a cluster of two or more applications, with a minimum of one application for a computational/modeling component and one application for a biomedical/experimental component of the cluster. Clusters may request project periods of up to three years and direct costs of up to $600,000 per year per entire cluster. • Application receipt dates: September 25, 2006 and September 25, 2007 (Letter of intent receipt dates: August 24, 2006 and August 24, 2007 • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-HL-07- 005.html. C. Using Metabolomics to Investigate Biological Pathways and Networks This NIH-wide initiative under the NIH Roadmap encourages the use of innovative metabolomics technologies to establish methods and model systems for advancing understanding of biological pathways and networks, their temporal and spatial resolution, and their regulation in health and disease states. Work should focus on breaking new ground or extending previous discoveries toward new directions or applications in basic, translational, or clinical research. This funding opportunity is part of the larger Roadmap effort to provide new sets of tools to explore biological pathways and networks (see http://nihroadmap.nih.gov/buildingblocks/). • NEW • Research project grant (R01) award mechanism • $3.8 million is allocated in FY2007 for approximately 7 to 10 awards. Applicants may request up to $350,000 direct costs per year for up to five years. • Application receipt date: October 20, 2006 (Letter of intent receipt date: September 22, 2006 • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-06- 010.html. A. Development of Nonmammalian Models and Related Biological Materials for Research The National Center for Research Resources seeks applications that propose to develop new non- mammalian research model systems or to expand on the usefulness of existing non-mammalian model systems such as fish and other lower vertebrates, invertebrates, microorganisms and cell and tissue culture systems. Models proposed must be relevant to the research interests of two or more categorical NIH Institutes. • CONTINUATION of ongoing program • Exploratory/developmental (R21) grant mechanism • A specific amount has not been set aside for this initiative, but will depend upon the merit of the submitted projects. Applicants may request up to $275,000 in direct costs for a two-year period. • Standard receipt dates apply (see http://grants.nih.gov/grants/funding/submissionschedule.htm) (Letter of intent not necessary) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 498.html. B. Assay Development for High Throughput Molecular Screening This NIH-wide initiative under the NIH Roadmap is to support development and adaptation of biological assays for automated high throughput molecular screening. This particular funding opportunity is one component of the NIH Molecular Libraries and Imaging Roadmap Initiative (http://nihroadmap.nih.gov/molecularlibraries/index.asp). A key purpose is to facilitate discovery of new molecular probes for investigating biological function. A companion notice solicits compounds for high throughput screening by the Molecular Libraries Screening Centers Network (http://grants.nih.gov/grants/guide/notice-files/NOT- RM-06-017.html). II. MODELS, MATERIALS, AND METHODS • CONTINUATION of ongoing program • Exploratory/developmental research grant (R21) award mechanism • Approximately $8 million is available in 2007 for 40 to 50 awards. Applicants may request up to $125,000 in direct costs for one year. • Application submission/receipt date on Grants.gov: September 22, 2006 (Letter of intent receipt date: September 8, 2006) • Submission format: SF424 form electronically through Grants.gov no earlier than August 22 The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-RM-07- 001.html. C. REQUEST FOR INFORMATION: Animal Model Resource Informatics The National Center for Research Resources seeks to obtain information on existing animal model resources and the informatics platforms used to support them. The information will be used in planning for a comprehensive electronic catalog of animal model resources and their associated data and access methods. The information will also be used for planning of research resource development. Investigators who develop and maintain animal resources relevant to biomedical research are asked for information on organizational and business aspects, functional capabilities, data and content, and technical and architecture of informatics. • NOTICE • Response deadline: August 25, 2006 The full notice, including NCRR point of contact, can be found at http://grants.nih.gov/grants/guide/notice-files/NOT-RR-06-003.html. D. REQUEST FOR INFORMATION: Tools and Resources for Research in Neurodevelopment The fifteen funding Institutes participating in the NIH Blueprint for Neuroscience Research (http://neuroscienceblueprint.nih.gov) solicit information on determining how best to accelerate research in developmental neuroscience. Responses to this notice should be pertinent to the interests of one or more of the NIH Institutes involved in the Neuroscience Blueprint. Comments pertaining to normal and/or atypical nervous system development are specifically encouraged. The NIH Blueprint goal for fiscal year 2008 is to generate novel research tools and resources to rapidly advance the field of neural development, so innovative and novel ideas are encouraged. • NOTICE • Response deadline: October 31, 2006 The full announcement can be found at http://grants.nih.gov/grants/guide/notice-files/NOT-MH- 06-114.html. E. Exfoliated Cells and Circulating DNA in Cancer Detection and Diagnosis The National Cancer Institute has expanded its funding opportunities to develop novel technologies for capturing, enriching, and preserving exfoliated abnormal cells and macromolecules in body fluids or effusions and to develop methods for concentrating the tumor- derived subcellular material for use in biomarker studies. In body fluids, such as sputum, exfoliated tumor cells are a minor component compared to normal cells. As a result, the detection of exfoliated abnormal cells by routine cytopathology is often limited by the small number of atypical cells present in a given specimen. New enrichment methods are necessary to facilitate the detection of small numbers of exfoliated tumor cells and tumor- derived sub-cellular materials in biological fluids. This funding opportunity runs in parallel with two of similar scientific scope that solicit applications under small business mechanisms (RFA-CA-07-027 and RFA-CA-07-028). Please refer to the NIH Guide Notice NOT-CA-06- 034 (http://grants.nih.gov/grants/guide/notice-files/NOT-CA-06-034.html) for the cross- comparison and the outline of the characteristics and requirements for all three announcements. • CONTINUATION of ongoing program • Exploratory/developmental grant (R21) mechanism • Two to three awards are anticipated, but no specific funding amounts are targeted. Applicants may request up to $275,000 direct costs for a two year project period, with no more than $200,000 in direct costs allowed in any single year. • Standard receipt dates apply (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 499.html. F. Technology Development for the Comprehensive Determination of Functional Elements in Eukaryotic Genomes The National Human Genome Research Institute solicits projects to develop new and improved technologies for efficient, comprehensive, high-throughput identification and validation of sequence-based functional elements in eukaryotic genomes. This technology development is a continuing component of the ENCODE (Encyclopedia of DNA Elements) project with a long- term goal of identifying all the functional elements in the human genome. • CONTINUATION and reconfiguration • Exploratory/developmental grant (R21) and research project grant (R01) mechanisms • Between six and ten awards will be made from the targeted $2 million in FY 2007. Applicants may request up to $200,000 direct costs for a two year project period, with no more than $100,000 in direct costs allowed in any single year for the R21 mechanism. R01 applicants may request a project period of up to three years and a budget for direct costs up to $350,000 dollars per year. • Application receipt date: November 28, 2006 (Letter of intent receipt date: October 30, 2006) • Submission format: SF424 form electronically through Grants.gov for R21 applications; PHS 398 application for R01 projects. The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-07- 028.html for R21 applications and at http://grants.nih.gov/grants/guide/rfa-files/RFA-HG-07- 029.html for R01 applications. G. Development and Application of PET and SPECT Imaging Ligands as Biomarkers for Drug Discovery and for Pathophysiological Studies of CNS Disorders The National Institute of Mental Health, National Institute on Aging, National Institute of Alcohol Abuse and Alcoholism, and National Institute on Drug Abuse hope to stimulate the development of radioligands for molecular targets (e.g. receptors, cell adhesion molecules, intracellular messengers, and disease related proteins) for research relevant to the pathophysiology of brain and behavioral disorders. A coordinated set of funding opportunities uses the phased innovation award mechanisms. Participating in some of the initiatives are the National Institute of Biomedical Imaging and Bioengineering (R21), the National Institute of Neurological Disorders and Stroke (R21/R33,R33, small business), and National Institute of Deafness and Other Communication Disorders (small business). • CONTINUATION and reconfiguration • Phased innovation grant (R21/R33), phase II exploratory/developmental grant (R33), exploratory/developmental grant (R21) and small business grant (SBIR, STTR) mechanisms • No designated funds are set aside. Specific budgetary guidance is provided for applicants for each specific mechanism • Standard receipt dates apply (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov The full announcements can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 463.html for R21/R33 applications, at http://grants.nih.gov/grants/guide/pa-files/PA-06- 461.html for R21 applications, and http://grants.nih.gov/grants/guide/pa-files/PA-06-462.html for R33 applications. Each announcement cross-references the small business solicitations. A. Enabling Technologies for Tissue Engineering and Regenerative Medicine Six NIH Institutes have collaborated with the National Institute of Standards and Technology (NIST) and the National Science Foundation (NSF) in issuing a funding opportunity announcement that solicits design or hypothesis-driven research applications to promote innovative technologies, tools, methods, and devices that will enable tissue engineering and regenerative medicine. Specific scientific interests include predictive computational models for engineering functional 3-dimensional tissues, 3-dimensional fabrication technologies for tissue engineering, novel bioreactors to control the chemical and mechanical environment, quantitative non-invasive tools to monitor structure, composition, and function of engineered tissues in real time, and technologies for manufacturing of tissue-engineered products. Each research partner at NIH (National Institute of Biomedical Imaging and Bioengineering, National Heart, Lung, and Blood Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institute of Child Health and Human Development, National Institute on Deafness and Other Communication Disorders, and National Institute of Dental and Craniofacial Research), at NIST (Chemical Science and Technology Laboratory and Materials Science and Engineering Laboratory), and at NSF (Division of Bioengineering and Environmental Systems) details their interest in the full solicitation. • NEW • Research project (R01) grant mechanism, with multiple principal investigator option • No specific amount is set aside, but meritorious applications will be supported. Applicants should propose a budget commensurate with the work proposed, based on details in the announcement. • Application submission/receipt dates: September 20, 2006, January 19, 2007, May 21, 2007 and similar dates through 2009 (Letter of intent receipt dates: August 21, 2006, December 20, 2006, April 23, 2007 and similar dates one month prior to the application receipt date) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06- 504.html III. BIOENGINEERING B. Bioengineering Research Partnerships Fourteen of NIH’s 27 institutes, with the National Institute of Biomedical Imaging and Bioengineering as lead contact, have noted their ongoing interest in receiving applications directed toward basic, applied, and translational bioengineering research with relevance for biology, medicine, behavior or health. Objectives of the program are also to foster collaborations and partnerships among allied quantitative and biomedical disciplines, including the fostering of a new generation of scientists capable of interacting across traditional technical boundaries. • CONTINUATION • Research project grant (R01) award mechanism. • No specific amount is set aside. NIH will not provide annual support in excess of $2 million total cost for any year for new applications. Some institutes have budget caps of less than $2 million total cost as noted at http://www.becon.nih.gov/becon_brpareas.htm. • Application receipt dates: September 20, 2006 and January 22, 2007 (Letter of intent receipt dates: August 20, 2006 and December 20, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06- 459.html. A. Long-Term Weight Maintenance: Basic and Clinical Studies The National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Nursing Research, National Institute on Aging, and the Office of Dietary Supplements indicate their ongoing interest in research that investigates the factors involved in long-term weight stability and/or weight regain after intentional weight loss, including studies in both animals and humans. Clinical studies investigating the role of behavioral, nutritional, exercise or other interventions in enhancing long-term weight maintenance will be supported. Collaborations between basic and clinical researchers are specifically encouraged. • CONTINUATION • Research project (R01) grant mechanism. A companion planning grant announcement of identical scientific scope (PA-06-144) utilizes the exploratory/developmental research grant (R21) mechanism and the SF424 electronic form. • No specific amount is set aside, but meritorious applications will be supported. Applicants should propose a budget commensurate with the work proposed. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 145.html. B. Translational Research for the Prevention and Control of Diabetes and Obesity The National Institute of Diabetes and Digestive and Kidney Diseases, National Institute of Nursing Research, and Office of Behavioral and Social Sciences Research have renewed their interest in funding projects that develop cost effective and sustainable interventions that can be adopted in real world settings, for the prevention and control of diabetes and obesity. The proposed research should be based on interventions already proved efficacious in clinical trials to prevent and reverse obesity and type 2 diabetes, to improve care of type 1 and type 2 diabetes, and to prevent or delay complications. IV. DIABETES AND OBESITY • CONTINUATION • Research demonstration and dissemination project (R18) award mechanism. A companion planning grant announcement of identical scientific scope (PAR-06-358) utilizes the translational research project grant (R34) mechanism and the SF424 electronic form. • No specific amount is set aside, but meritorious applications will be supported. Applicants should propose a budget commensurate with the work proposed for a period of no more than five years. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06- 457.html. C. Diet Composition and Energy Balance Eight institutes and the Office of Dietary Supplements are supporting work on diet composition in energy balance, including studies in both animals and humans. Both short and longer-term studies are appropriate, ranging from basic studies investigating the impact of micro- or macronutrient composition on appetite, metabolism, and energy expenditure through clinical studies evaluating the efficacy of diets differing in micro- or macronutrient composition, absorption, dietary variety, or energy density for weight loss or weight maintenance. • CONTINUATION, with expiration date of November 2, 2006 • Research project grant (R01) and exploratory/developmental (R21) award mechanisms • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R21 applications; PHS 398 application for R01 projects. The full announcements can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 173.html for R01 applications and http://grants.nih.gov/grants/guide/pa-files/PA-06-174.html for R21 applications. D. Heterogeneity of Fat Depots: Underlying Basis and Association with Morbidity The National Institute of Diabetes and Digestive and Kidney Diseases, National Heart, Lung, and Blood Institute and National Institute on Aging request applications to investigate the life cycle of adipocytes and other cell types present in various fat depots, such as macrophages, neurons, and endothelial cells. The goal of this initiative is to increase understanding of the interactions among the cell populations in order to identify biomarkers of changes in cellular physiology and metabolism brought on by the obese state. • CONTINUATION, with expiration date of March 2, 2007 • Research project grant (R01) and exploratory/developmental (R21) award mechanisms • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R21 applications; PHS 398 application for R01 projects. The full announcements can be found at http://grants.nih.gov/grants/guide/PA-files/PA-06- 186.html for R01 applications and http://grants.nih.gov/grants/guide/pa-files/PA-06-187.html for R21 applications. E. Exploratory/Developmental Clinical Research Grants in Obesity The National Institute of Diabetes and Digestive and Kidney Diseases, National Heart, Lung, and Blood Institute, National Cancer Institute, and Office of Dietary Supplements request applications to encourage exploratory/developmental clinical studies that will accelerate the development of effective interventions for prevention or treatment of overweight or obesity in either adults or children. Exploratory epidemiological research with a goal of informing translational/clinical research will also be supported within this program • CONTINUATION and EXPANSION • Exploratory/developmental (R21) award mechanisms. • No specific amounts are set aside, but meritorious applications will be supported. Applicants may request a project period of up to 2 years with a combined budget for direct costs of up $275,000 for the 2-year period. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 256.html. F. Pilot and Feasibility Clinical Research Studies in Digestive Diseases and Nutrition The National Institute of Diabetes and Digestive and Kidney Diseases requests pilot and feasibility clinical and epidemiological research studies of new therapies or means of prevention of digestive and liver diseases and nutritional disorders associated with digestive and liver diseases. • CONTINUATION and EXPANSION • Exploratory/developmental (R21) award mechanisms. • No specific amounts are set aside, but meritorious applications will be supported. Applicants may request a project period of up to 2 years with a combined budget for direct costs of up $275,000 for the 2-year period. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 301.html. G. Diabetes Research Centers The National Institute of Diabetes and Digestive and Kidney Diseases continues its program of supporting Diabetes Research Centers to provide shared access to specialized technical resources and expertise, and to provide a framework for enhancing translational research. Diabetes Endocrinology Research Centers (DERCs) support biomedical research cores, pilot and feasibility projects, and interdisciplinary interaction and training of investigators. The Diabetes Research and Training Centers (DRTC) provide the above elements plus an additional focus on diabetes prevention and control research. • CONTINUATION of ongoing program • Core center (P30) and comprehensive center (P60) award mechanisms • $14.9 million dollars are committed in FY2007 to fund 8 to 10 new or competing continuation grants. Applicants for a DERC may request up to $1 million dollars per year for a project period of five years. Applicants for a DRTC may request up to $1.25 million dollars per year for up to five years. Additional amounts may be requested for work with underserved populations. • Application receipt date: December 18, 2006 (Letter of intent receipt date: November 17, 2006) • Submission format: PHS 398 grant application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-DK-06- 014.html. H. Additional Major Affiliates needed to Join the Type 1 Diabetes TrialNet Clinical Network The National Institute of Diabetes and Digestive and Kidney Diseases will be expanding its clinical trial network of affiliate sites by identifying additional institutes that are prepared to serve as a Major Affiliate. These affiliates provide direct TrialNet presence in communities that do not now have a Clinical Center or Major Affiliate and serve as clinical sites for treatment and follow-up for the TrialNet studies. Major Affiliates receive direct infrastructure funding and reimbursement for patient care costs via a subcontract with the TrialNet Coordinating Center. Additional information on TrialNet is at http://www.diabetestrialnet.org/hindex.html. • EXPANSION • Deadline: September 1, 2006 • Instructions for submitting proposals to the Coordinating Center at http://www.diabetestrialnet.org/rfs.pdf. I. School-based Interventions to Prevent Obesity The National Institute of Child Health and Human Development, National Institute of Diabetes and Digestive and Kidney Diseases, National Cancer Institute, and Office of Behavioral and Social Sciences Research have issued three companion solicitations to encourage the formation of partnerships between academic institutions and school systems in order to develop and implement controlled, school-based intervention strategies designed to reduce the prevalence of obesity in childhood. This initiative also encourages evaluative comparisons of different intervention strategies, as well as the use of methods to detect synergistic interactions between different types of interventions. • CONTINUATION and reconfiguration of program • Research project grant (R01), exploratory/developmental (R21) and small grant (R03) award mechanisms. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R03 and R21 applications; PHS 398 application for R01 projects. The full announcements can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 415.html for R01 applications, http://grants.nih.gov/grants/guide/pa-files/PA-06-417.html for R21 applications, and http://grants.nih.gov/grants/guide/pa-files/PA-06-416.html for R03 applications. A. Cooperative Research Partnerships into Therapeutics and Diagnostics for Biodefense Toxins The National Institute of Allergy and Infectious Diseases requests research projects that will address discovery, design, and/or development of novel therapeutics and/or post-exposure prophylactics and rapid and sensitive diagnostics for certain biodefense toxins: Shiga toxins, ricin toxin, Staphylococcus entertoxin B, Clostridium perfringens epsilon toxin and the botulinum neurotoxins. Translational research to support, or which might lead to, the development of therapeutics or diagnostics for biodefense toxins as well as advance product development are sought. Applications that include collaborations between researchers from different disciplines and/or with industry are encouraged. Basic research will not be supported under this solicitation. • NEW • Cooperative agreement (U01) grant mechanism • Approximately $10 million in FY2007 is committed to support 10to 15 awards. Applicants may request up to $500,000 direct costs per year for up to five years. • Application receipt date: November 27, 2006 (Letter of intent receipt date: October 27, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-06- 035.html B. NIAID Partnerships with Public-Private Partnerships This particular initiative will support collaborative relationships between the National Institute of Allergy and Infectious Diseases and established product development Public-Private Partnerships in order to accelerate preclinical research and development of promising new preventive, therapeutic, or diagnostic tools. These projects should target high priority neglected infectious diseases of global importance for which commercial markets currently provide insufficient incentive for corporate investment. • NEW V. RESEARCH PARTNERSHIPS IN BIODEFENSE AND INFECTIOUS DISEASES • Cooperative agreement (U01) award mechanism • Approximately $3 million is available in FY 2007 to fund 3 to 4 new cooperative agreements. Applicants may request a project period of up to five years and a budget commensurate with the work proposed. • Application receipt date: November 30, 2006 (Letter of intent receipt date: October 30, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-AI-06- 033.html. A. NIAMS Clinical Trial Outcomes Instrument Development Grant Program The National Institute of Arthritis, Musculoskeletal and Skin Diseases encourages projects that propose to design, evaluate, validate, and test new and/or improved outcome measures for clinical trials in diseases, illnesses and injuries of interest to the institute. Experimental designs may include consensus development approaches, meetings of experts, collection data, beta testing of new instruments, mathematical and computer modeling, and validation studies. • NEW • Cooperative agreement (U01) award mechanism • Approximately $1 million is committed to fund four or five new cooperative agreements. Applicants may request a project period of up to three years and a budget for direct costs up to $150,000 per year. • Application receipt date: August 29, 2006 (Letter of intent receipt date: July 29, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-AR-06- 006.html. B. Innovative Therapies and Clinical Studies for Screenable Disorders The National Institute of Child Health and Human Development, National Institute on Deafness and Other Communication Disorders, and National Institute of Diabetes and Digestive and Kidney Diseases have indicated their ongoing interest in stimulating translation research on potential therapeutic interventions for currently screened conditions and high priority genetic conditions for which screening could be possible in the near future. Special emphasis is placed on research relating to some of the high priority conditions identified in a recent report on newborn screening (http://mchb.hrsa.gov/screening). • CONTINUATION • Exploratory/developmental (R21) award mechanism • No specific funds are targeted. Applicants may request up to $275,000 direct costs for a VI. NEW APPROACHES TO CLINICAL STUDIES two year project period. • Standard receipt dates apply, letters of intent requested 30 days prior. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06- 342.html. This announcement cross references two additional solicitations of identical scope targeted to the research project grant (R01) and small grant (R03) mechanisms. C. Specialized Programs of Research Excellence (SPOREs) in Human Cancer for the Year 2007 The National Cancer Institute continues its SPORE program of state-of-the-art research that will contribute to improved screening, detection, diagnosis, treatment, and prevention of an organ- specific cancer or related group of cancers. SPOREs are expected to conduct a wide spectrum of research activities, and develop specialized research cores, improved research model systems, and collaborative research projects with other institutions. The work must be translational in nature. • CONTINUATION of ongoing program • Specialized center (P50) grant mechanism • There is no specific set aside for this program. Applicants may request a maximum annual total cost of $2.5 million for up to five years. • Application receipt dates: January 23, 2007, May 22, 2007, September 21, 2007 (Letters of intent receipt dates: December 23, 2006; April 22, 2007; August 21, 2007) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06- 505.html. D. Specialized Centers of Interdisciplinary Research (SCOR) on Sex and Gender Factors Affecting Women’s Health Six Institutes in partnership with the Office of Research on Women’s Health have issued the second solicitation for centers to develop research agendas bridging basic and clinical research on sex/gender factors underlying a health issue that affects women. Each center should present at least three individual but interrelated research projects as well as an administrative core. Support will not be provided for large clinical trials or for work that is exclusively clinical or exclusively basic. • CONTINUATION and expansion • Specialized center (P50) grant mechanism • At least $10 million is committed in FY 2007 to fund approximately 10 new and/or competing continuation applications. An applicant may request a project period of up to five years and a budget for direst costs of up to $750,000 in the first year. • Application receipt date: September 14, 2006 (Letter of intent receipt date: August 14, 2006) • Submission format: PHS 398 application The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-OD-06- 003.html. A. Neuroeconomics of Aging The National Institute on Aging has issued a solicitation to stimulate investigations in the neuroeconomics of aging. The institute seeks projects examining the social, emotional, cognitive, motivational process and neurobiological mechanisms of economic behavior. Of particular interest are social, financial, and health-related decisions affecting the well-being of middle-aged and older adults and the development and refinement of integrative economic theories of utility, learning, and strategic choice relevant to aging.” • NEW • Exploratory/developmental (R21) award mechanism • Approximately $1.5 million is committed to fund four to six grants. The total project period for an application submitted in response to this funding opportunity may not exceed three years. Direct costs are limited to $350,000 over a three-year period, with no more than $200,000 in direct costs allowed in any single year. • Application submission/receipt date: November 27, 2006 (Letter of intent receipt date: October 30, 2006) • Submission format: SF424 form electronically through Grants.gov The full announcement can be found at http://grants.nih.gov/grants/guide/rfa-files/RFA-AG-06- 011.html. B. Behavioral and Social Research on Disasters and Health The National Institute on Aging, National Institute of Nursing Research, National Institute of Child Health and Human Development, and Office of Behavioral and Social Science Research are interested in stimulating research in the behavioral and social sciences on the consequences of natural and man-made disasters for the health of children, the elderly, and vulnerable groups, with an ultimate goal of preventing or mitigating harmful consequences. Examples of disasters include severe weather-related events, earthquakes, large-scale attacks on civilian populations, technological catastrophes or perceived catastrophes, and influenza pandemics. • NEW VII. ECONOMICS, HEALTH SERVICES, AND INTEGRATIVE TREATMENT • Research project grant (R01), exploratory/developmental (R21), and small grant (R03) award mechanisms. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R21 and R03; PHS 398 for R01 applications The full announcements can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 454.html for R01 applications, http://grants.nih.gov/grants/guide/pa-files/PA-06-452.html for R21 applications, and http://grants.nih.gov/grants/guide/pa-files/PA-06-453.html for R03 applications. C. Health Services Research on Practice Improvement Utilizing Community Treatment Programs within the National Drug Abuse Clinical Trials Network The National Institute on Drug Abuse has established a research partnership between more than 150 community treatment programs and drug abuse researchers in multiple sites. With its extensive network of providers serving diverse populations of drug users, this network provides an infrastructure for the investigation of (a) systems-level factors that facilitate practice improvement in community treatment programs, and (b) new research tools to facilitate higher quality health services research on practice improvement in drug abuse treatment. The institute notes that, in seeking new projects in this area, there are multiple aspects to practice improvement for drug abuse treatment. In community settings, adoption and implementation of evidence-based practices is a complex multidirectional process of continuous practice enhancement that involves interaction among multiple individual-, organizational-, and contextual-level factors. Exploratory and pilot projects are sought. • CONTINUATION and reformulation of ongoing program • Research project grant (R01), exploratory/developmental (R21), and small grant (R03) award mechanisms. • Standard receipt dates apply (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R21 and R03; PHS 398 for R01 applications The full announcements are at http://grants.nih.gov/grants/guide/pa-files/PA-06-495.html for R01 applications, http://grants.nih.gov/grants/guide/pa-files/PA-06-496.html for R21, and http://grants.nih.gov/grants/guide/pa-files/PA-06-497.html for R03 applications. D. Behavioral and Integrative Treatment Development Program The National Institute on Drug Abuse, the National Institute on Alcohol Abuse and Alcoholism, and the National Center for Complementary and Alternative Medicine are seeking research grant applications on the development and testing of behavioral and integrative treatments for drug and alcohol abuse and dependence. The term "behavioral treatments" includes various forms of psychotherapy, behavior therapy, cognitive therapy, family therapy, couples and marital therapy, group therapy, skills training, meditation, yoga, tai chi (taiji), guided imagery, counseling, and rehabilitative therapies. The term “integrative treatments” refers to treatments that combine behavioral interventions with other treatments, including other behavioral therapies, medications, and/or complementary/alternative therapies. Behavioral and integrative treatment research has been conceptualized, for the purpose of this initiative, to consist of three stages: early treatment development, testing treatments that show promise and the “dose-response” of treatments, and research aimed at determining if and how efficacious behavioral treatments may be transported to community settings. Determination of mechanism of action of treatment is relevant to all three stages. • CONTINUATION and reformulation of ongoing program • Research project grant (R01), exploratory/developmental (R21), and small grant (R03) award mechanisms. • Standard receipt dates apply. (see http://grants.nih.gov/grants/funding/submissionschedule.htm) • Submission format: SF424 form electronically through Grants.gov for R21 and R03; PHS 398 for R01 applications The full announcements can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06- 486.html for R01 applications, http://grants.nih.gov/grants/guide/pa-files/PA-06-487.html for R21 applications, and http://grants.nih.gov/grants/guide/pa-files/PA-06-488.html for R03 applications. E. Mental Health Issues in Communities The National Institute on Mental Health has issued six research project (R01) grant solicitations that address several aspects of mental health at various life stages and in different conditions. They are listed below: • Pathophysiology and Treatment Response in Late-Life Mood and Anxiety Disorders Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-489.html. • Research on Community Reintegration for People with Psychiatric Disabilities Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-427.html • Research on Psychopathology in Intellectual Disabilities (Mental Retardation) Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-431.html • Research on Rural Mental Health and Drug Abuse Disorders (in partnership with the National Institute on Drug Abuse) Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-478.html • Research on the Reduction and Prevention of Suicidality (in partnership with the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism) Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-438.html • Risk Factors for Psychopathology Using Existing Data Sets (in partnership with the National Institute on Drug Abuse and the National Institute on Alcohol Abuse and Alcoholism) Full announcement at http://grants.nih.gov/grants/guide/pa-files/PA-06-439.html A. New Policy for Funding of Tuition, Fees, and Health Insurance on Ruth L. Kirschstein National Research Service Awards For new and renewal institutional research training grants (T32, T34, and T35) and competing individual fellowships (F30, F31, F32, and F33) under the Ruth L. Kirschstein National Research Service Awards (NRSA) program, NIH has announced a change in policy for tuition, fees, and health insurance costs. These changes will begin in fiscal year FY 2007 for both newly awarded NRSAs and for noncompeting institutional NRSAs. A summary of the changes follows. For institutional training grants: • Tuition and fees: An amount per predoctoral trainee equal to 60 percent of the level requested by the applicant institution, up to $16,000 per year, will be provided. For combined dual-degree training (e.g. M.D-Ph.D./ D.D.S.-Ph.D.), up to $21,000 will be provided. For postdoctoral trainees, 60 percent of the level requested, up to $4500 per year, will be provided. • Training related expenses: Health insurance is an allowable expense. An additional $2000 per predoctoral trainee, per year, and an additional $4000 per postdoctoral trainee, per year, will be provided. For individual postdoctoral fellowships: • Predoctoral institutional allowance: An additional $1450 per predoctoral fellow per year will be provided for health insurance as an allowable expense. • Postdoctoral institutional allowance: This category already includes health insurance as an allowable cost, but is now adjusted by an additional $850 per postdoctoral fellow per year, to be comparable with the institutional training grants. More details may be viewed in NIH’s official notice at http://grants.nih.gov/grants/guide/notice- files/NOT-OD-06-090.html. The full description of NIH’s recently reissued announcement for the NRSA Institutional Research Training Grants (T32) is at http://grants.nih.gov/grants/guide/pa-files/PA-06-468.html. NIH has also announced that individual postdoctoral fellowship applications (F32) will be subjected to the agency’s streamlined review process at http://grants.nih.gov/grants/guide/notice-files/NOT-OD-06- 077.html. VIII. PRE- AND POSTDOCTORAL TRAINING B. Predoctoral Training at the Interface of the Behavioral and Biomedical Sciences The National Institute of General Medical Sciences has announced a new predoctoral institutional research training grant program to develop basic behavioral scientists with rigorous broad-based training in the biomedical sciences. Equal participation of both biomedical and behavioral faculty should provide an interdisciplinary research training experience and curriculum. The primary focus is on training students with previous behavioral training and/or who are enrolled in behavioral sciences graduate departments. • NEW • Institutional National Research Service Award (T32) mechanism • Approximately five to ten training grants will be awarded. • Application submission dates: October 24, 2006, September 10, 2007, September 10, 2008. (Letters of intent dues: September 24, 2006, August 10, 2007, August 10, 2008) • Submission format: PHS 398 grant application The full announcement, including details of budget preparation, can be found at http://grants.nih.gov/grants/guide/pa-files/PAR-06-503.html C. Ruth L. Kirschstein National Research Service Awards for Individual Predoctoral Fellowships to Promote Diversity in Health-Related Research Twenty one of NIH’s institutes and centers will support training of predoctoral students from groups that have been shown to be underrepresented, such as underrepresented racial and ethnic groups, individuals with disabilities, and individuals from disadvantaged backgrounds. • NEW • Individual predoctoral fellowship award (F31) mechanism • Stipends, tuition and fees and an institutional allowance are provided. NIH has not specified the number of awards anticipated. • Application receipt dates: May 1, November 15 (Letters of intent are not necessary.) • Submission format: PHS 416-1 individual fellowship application The full announcement, including details of eligibility, can be found at http://grants.nih.gov/grants/guide/pa-files/PA-06-481.html . –END- Date submitted: Mon, 14 Aug 2006 13:24:41 -0700 (PDT)
Website:	http://grants.nih.gov/grants/guide/pa-files/PA-06-481.html
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Mon, 14 Aug 2006 13:24:41 -0700 (PDT)

Title of notice	Department of the Army Research Instrumentation Grant
Notice type:	Request for proposals
Grant type:	Research
Research type:	Basic science
Funding type:	Federal
Years of support:	None given
Due date:	None given
Description:	Printer-friendly
	Program Number: 08542 Title: Research Instrumentation Grants Sponsor: Department of the Army SYNOPSIS: Support is provided to U.S. universities that are current holders of research grants or contracts, to purchase instrumentation in support of the research or to develop new research capabilities in the areas important to national defense. Deadline(s): Established Date: 03/04/1992 Follow-Up Date: 11/01/2007 Review Date: 11/13/2006 Contact: Kathryn McManus Address: U.S. Army Research Office P.O. Box 12211 Research Triangle Park, NC 27709-2211 U.S.A. E-mail: Kathryn.McManus@us.army.mil Web Site: http://www.arl.army.mil/main/main/DownloadedInternetPages/CurrentPages/DoingBusinesswithARL/research/AROBAA1102.doc Program URL: http://www.grants.gov/search/search.do?oppId=11441&mode=VIEW Tel: 919-549-4264 Fax: Deadline Ind: Receipt Deadline Open: Yes Award Type(s): Equipment Citizenship/Country of Applying Institution: Any/No Restrictions Locations Tenable: U.S.A. Institution (including U.S. Territories) Appl Type(s): Colleges/Universities Target Group(s): NONE Funding Limit: $0 NOT PROV Duration: 0 Indirect Costs: No Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 12.431 OBJECTIVES: Support is provided to improve the capabilities of U.S. universities to conduct research and educate scientists and engineers in areas important to national defense. Funds may be used to purchase instrumentation in support of this research or in the development of new research capabilities. Areas of interest include chemistry, electronics, environmental sciences, life sciences, mathematical and computer sciences, mechanical sciences, materials science, and physics. ELIGIBILITY Eligible colleges and universities must have a current grant or contract with the sponsor. Source: Grants.gov (11/06/06). (cmb) Date submitted: Fri, 17 Nov 2006 14:25:50 -0800 (PST)
Website:	http://www.grants.gov/search/search.do?oppId=11441&mode=VIEW
USC contact:	Gigi Petrovich, gpetrov@usc.edu, 323-442-1607
Date submitted:	Fri, 17 Nov 2006 14:25:50 -0800 (PST)

Title of notice	National Cancer Institute/NIH/DHHS Stem Cells and Cancer (R01)
Notice type:	Request for proposals
Grant type:	Research
Research type:	Basic science and Clinical
Funding type:	Federal
Years of support:	5 years
Due date:	Jun 05, 2007
Description:	Printer-friendly
	Program Number: 83091 Title: Stem Cells and Cancer (R01) Sponsor: National Cancer Institute/NIH/DHHS SYNOPSIS: The sponsor offers support for research on all aspects of stem cell biology, including research into the molecular and biochemical regulation of embryonic and adult stem cell behavior, with the goal of ultimately improving the specificity and long-term effectiveness of cancer therapy, through the targeting of those cells most responsible for disease progression and metastasis. This program will use the NIH Research Project (R01) award mechanism. <S2S> Deadline(s): 06/05/2007 10/05/2007 02/05/2008 05/07/2007 09/07/2007 01/07/2008 05/07/2008 Established Date: 04/13/2005 Follow-Up Date: 02/01/2008 Review Date: 03/09/2007 Contact: R. Allan Mufson, Ph.D., Chief Address: Cancer Immunology Hematology Branch, Division of Cancer Biology 6130 Executive Blvd. EPN Room 5062, MSC 7388 Bethesda, MD 20892-7388 U.S.A. E-mail: am214t@nih.gov Program URL: http://grants1.nih.gov/grants/guide/pa-files/PA-07-187.html Tel: 301-496-7815 Fax: 301-480-2844 Deadline Ind: Receipt Deadline Open: No *See Restrictions for further information. DEADLINE NOTE The deadlines for receipt of standard R01 applications under this announcement are: February 5, June 5, and October 5 annually. The deadlines for receipt of AIDS-related applications are: January 7, May 7, and September 7 annually. This program will expire on May 8, 2008. Award Type(s): Research Grants/R & D Citizenship/Country of Applying Institution: Any/No Restrictions Locations Tenable: Any/No Restrictions Appl Type(s): Colleges/Universities For-Profit Hospital Laboratory Non-Profit Organizations--Community/Soc. Serv. Organizations--Health/Medical Private Institution/Organization Public Institution Research Institutions/Organizations Researcher/Investigator School of Medicine State/Local Agencies HBCU Indian Tribes/Governing Orgs. Minority Institution/Organization Small Business Tax-exempt Target Group(s): NONE Funding Limit: $0 NOT PROV Duration: 5 YEAR(s) Indirect Costs: Unspecified Cost Sharing: No Sponsor Type: Federal Geo. Restricted: NO RESTRICTIONS CFDA#: 99.999

Research Funding Opportunites - Current Notices

Office of Scientific Affairs, Keck School of Medicine

Francis S. Markland Jr, PhD, Associate Dean

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