Alzheimer Disease Research Center (ADRC)

• Grant Number : 5 P01 AG05142

• Principal Investigator : HC Chui

• Associate Director : CE Finch

• 04/01/99 - 03/31/04,  $4,434,191 total directs

• 04/01/03 - 03/31/04, $1,048,379 current year directs 

The ADRC project focuses on the molecular and cellular analysis of changes during 
Alzheimers disease  and on clinical methods for early detection and the identification of 
subtypes. No overlap.  No adjustment  necessary.

Training in Endocrinology and Neurobiology of Aging (NIH/NIA)

The training grant provides pre and post doctoral training for research careers on
basic mechanisms in the neural and endocrine changes of aging and related clinical
disorders such as Alzheimers disease.  No overlap.  No adjustment necessary.  

Models of Estrogen Interactions with Alzheimer Disease  

• Grant Number : 5 PO1 AG14751

• Principal Investigator : CE Finch

•  08/01/02-07/31/07, $4,307,418 total funds,

•  08/01/02-07/31/04,  $741,761 current year directs

The estrogen project project aims are to conduct experiments on rodent models in vivo
and in vitro to analyze mechanisms by which estrogens interact with neurons and glia
to modify synaptic plasticity. No overlap. No adjustment necessary

Caloric Restriction and Inflammatory Mechanisms

• Principal Investigator:  CE Finch 

• Alzheimer Association, Temple Award,

• 07/01/01-6/30/03, $227,267 total directs

• 07/01/02-6/30/03, $111,798 current year directs

This study will examine if caloric restriction can attenuate inflammatory changes during
aging in transgenic mouse models of Alzheimer disease. No  overlap .No adjustment
 necessary

ApoJ, (Clusterin) in Alzheimer Disease and Aging 

• Grant Number : NIA, R01 AG13499

• Principal Investigator : CE Finch

• 04/01/02 – 03/31/07, $1,712,384 total directs

• 04/01/03 – 03/31/04, $258,577 current year directs

The ApoJ project aims are to study the interactions of A beta with apoJ and apoE
and their expression and to study the regulation of apoJ by hormones.  No overlap.
No adjustment necessary