Dr. Stanley Azen, PhD, is the Director of the Statistical Consultation and Research Center, and Professor and Co-Director of Biostatistics in the Department of Preventive Medicine at USC. He also holds joint appointments in Ophthalmology and Biokinesiology & PT and serves as Assistant Dean for Academic and Scientific Affairs at the USC Keck School of Medicine. Dr. Azen is a Fellow of both the American Statistical Association and the International Statistics Institute, and has been the Editor-in-Chief of Computational Statistics and Data Analysis for over 20 years. He is currently involved in several research projects funded by the NIA, the National Eye Institute and the Environmental Protection Agency.
Positions & HonorsPositions
|2000-present||Assistant Dean, Academic and Scientific Affairs, Keck School of Medicine, University of Southern California|
|1991-present||Director, Statistical Consultation and Research Center, Department of Preventive Medicine, University of Southern California|
|1983-present||Editor-in-Chief, Computational Statistics and Data Analysis, official journal of the International Association of Statistical Computing|
|1980-present||Professor and Co-Director of Biostatistics, Department of Preventive Medicine. Joint appointments in Departments of Ophthalmology, Biokinesiology and Physical Therapy, University of Southern California|
Selected Honors & Awards
|2006||Honorary Doctorate, University of Salerno, Italy|
|2004||Alumni Hall of Fame, UCLA School of Public Health|
|2001||Fellow, International Statistics Institute|
|1998||Associates' Award for Excellence in Teaching|
|1993||Fellow, American Statistical Association|
|University of California, Los Angeles||Ph.D.||1969||Biostatistics|
|University of California, Los Angeles||M.A.||1962||Mathematics|
|University of California, Los Angeles||B.A.||1960||Mathematics|
Selected Current Research Projects
1 T32 GM 67546-01 (Azen) 04/01/06 - 03/31/11 NIH/NIEHS
Training Grant in Genomics Analysis and Interpretation
To provide multidisciplinary training for three predoctoral scientists and two postdoctoral scientists in specialized training at the interface between environmental health and genomics. Extensive research resources are available in support of studying gene-environment and gene-gene interactions in cancer and other diseases.
Role: Principal Investigator
5U10 EY 014472-05 (PI: Varma) 09/30/02 - 1/31/10 NIH/NEI
Multiethnic Pediatric Eye Disease Study (MEPEDS)
The primary objective of this study is to improve our understanding of the magnitude and causes of ocular disease problems in population-based samples of African-American, Latino and Non-Hispanic White children in the United States.
5R01 HL063963-05 (PI: Detrano) 12/01/99 - 08/31/08 (extended to 2010) NIH/NHLBI
Subcontract to Harbor UCLA Research and Educational Institute
Long Term Effects of Subclinical CAD on Cardiac Function
To provide management, reporting and statistical analyses of data arising from the South Bay Heart Watch (SBHW) cohort.
Role: Principal Investigator
5 R01 AG021108-02 (PI: Clark) 05/01/04 - 04/30/08 (extended to 2010) NIH/NIA
Health Mediating Effects of the Well Elderly Program
The objective of this study is to replicate the original Well Elderly Study, which demonstrated the benefit of a lifestyle redesign program on quality of life in a multi-ethnic cohort of participants aged 60 years or older. In addition, this study will examine the mediating mechanisms responsible for the change.
1 R01 NS050506-01A1 (PI: Duncan) 9/25/05 - 6/30/10 NIH/NINDS
Locomotor experience applied post-stroke (LEAPS)
Collection, management, reporting, and statistical analyses of data arising from the LEAPS trial. Provide data management and statistical support to meet the objectives of the proposal.
1 1 U54 CA 116848-01 (Goran) 09/19/05 - 8/31/10 NIH/NCI
USC Center for Transdisciplinary Research on Energetics and Cancer
To establish a trans-disciplinary center to address the physiologic, metabolic, behavioral, genetic and environmental influences on obesity, metabolic health and cancer risk with a focus on minority children. The center supports 3 projects, support cores, training and pilot studies. Project 1 will compare 40 African American and 40 Hispanic adolescents for various metabolic parameters and then examine the effects of a 16-week strength training intervention.
2P50CA084735-069002 (Azen) 09/30/99 - 08/31/09 NIH/NCI
Core 2: Statistics Core Genes, Environment and Tobacco Use Across Cultures (TTURC)
To provide data management and statistical support for on-going tasks for project in the center. To maintain a fast multi-processor computer and web-based server that are accessible directly or through the campus network by all TTURC investigators. To carry out psychometrics analyses and quality control on data collection process. The core will also conduct methodological research resulting from statistical issues arising from the research programs of the TTURC.
ROLE: Co- Investigator
R01 NS056256-01 (Carolee Winstein, PhD) 08/01/08-07/31/12 NIH/NINDS
Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (I-CARE)
The primary objective of I-CARE to conduct a 5 year, phase III, single-blind, multi-site randomized clinical trial to investigate the efficacy of focused upper extremity training that includes 30 hours of task-specific practice delivered during the earliest post-acute out-patient interval, one-three months post stroke.
ROLE: Co-Investigator Co-Director of Biostatistics Core/ S. Azen/2008-12
5P30EY003040-25 (Trousdale) 07/01/08– 06/30/09 NIH/NEI (Doheny Eye Institute)
Core Grant for Vision Research
Biometry Module-To provide assistance to Doheny Eye Institute (DEI) investigators in design, preparation of proposals, data analysis; training in principles of design and analysis of clinical and experimental studies; methodological research resulting from biostatistical issues arising from the clinical and basic research programs of the DEI.
ROLE: Director, Biometry Module
- Sattler FR, Castaneda-Sceppa C, Binder EF, Schroeder ET, Wang Y, Bhasin S, Kawakubo M, Stewart Y, Yarasheski KE, Ulloor J, Colletti P, Roubenoff R, Azen SP. Testosterone and growth hormone improve body composition and muscle performance in older men: The HORMA Trial. Journal of Clinical Endocrinology and Metabolism (in press).
- Hodis HN, Mack WJ, Dustin L, Mahrer PR, Azen SP, Detrano R, Selhub J, Alaupovic P, Liu C-L, Liu C-H, Hwang J, Wilcox AG, Selzer RH for the BVAIT Research Group. High-dose B-vitamin supplementation and progression of subclinical atherosclerosis: A randomized controlled trial (BVAIT). Stroke 40:730-37, 2009.
- Varma R, Mohanty SA, Deneen J, Wu J, Azen SP and the LALES Group. Burden and predictors of undetected eye disease in Mexican-Americans: The Los Angeles Latino Eye Study. Medical Care 46:497-506, 2008.
- Winstein C, Baurley J, Pate P, Ervin C, Underwood S, Ge T, Azen SP. The Physical Therapy Clinical Research Network (PTClinResNet): methods, efficacy and benefits of a rehabilitation research network. American Journal of Physical Medicine & Rehabilitation 87:xxx-xxx, 2008.
- Tarczy-Hornoch K, Lin J, Deneen J, Cotter SA, Azen SP, Borchert MS, Varma R, Wang Y and the Multi-Ethnic Pediatric Eye Disease Study Group. Stereoacuity testability in African-American and Hispanic preschool children: The Multi-Ethnic Pediatric Eye Disease Study. Optometry and Vision Science. 85:158-63, 2008.
- Duncan PW, Sullivan K, Behrman A, Azen SP, Wu, SS Nadeau SE, Dobkin B, Rose D, Tilson J for the LEAPS Investigative Team. Protocol for the Locomotor Experience Applied Post-Stroke (LEAPS) trail: A randomized control trial. Biomed Central Neurology 7 (39): 1-23, 2008.
- Hoki SL, Varma R, Lai M-Y, Azen SP, Klein R and the Los Angeles Latino Eye Study Group. Prevalence and associations of retinal emboli in Latinos: The Los Angeles Latino Eye Study (LALES). American Journal of Ophthalmology 145:143-8, 2008.
- Fraser-Bell S, Wu J, Klein R, Azen SP, Hooper C, Foong AWP, Varma R and the Los Angeles Latino Eye Study Group. Cardiovascular risk factors and age-related macular degeneration: The Los Angeles Latino Eye Study. American Journal of Ophthalmology 145:308-16, 2008.
- Cotter SA, Tarchy-Hornoch K, Wang Y, Azen SP, DiLauro A, Borchert M, Varma R, and the MEPEDS Group. Visual acuity testability in African-American & Hispanic Children: The Multi-Ethnic Pediatric Eye Disease Study. American Journal of Ophthalmology 144: 663-7, 2007.
- Schroeder ET, Castaneda-Sceppa C, Wang Y, Binder EF, Kawakubo M, Stewart Y, Storer T, Roubinoff R, Bhasin S, Yarasheski KE, Sattler FR, Azen SP. Hormonal regulators of muscle and metabolism in aging (HORMA): Design and conduct of a complex, double masked multicenter trial. Clinical Trials 4:560-71, 2007.
- McKean-Cowdin R, Varma R, Wu J, Hays RD, Azen SP, and Los Angeles Latino Eye Study Group. Severity of Visual Field Loss and Health-related Quality of Life. Am J Opthalmol, 143(6): 1013-1023, 2007.
- Schroeder ET, Wang Y, Castaneda-Sceppa C, Cloutier G, Vallejo AF, Kawakubo M. Jensky NE, Coomber S, Azen SP, Sattler FR. Reliability of Maximal Voluntary Muscle Strength and Power Testing in Older Men. J Gerontology Med Sci, 62:543-549, 2007.
- Fowler EG, Knutson LM, DeMuth SK, Sugi M, Siebert K, Simms V, Azen SP, Winstein CJ. Pediatric Endurance and Limb Strengthening for Children with Cerebral Palsy (PEDALS) – A Randomized Controlled Trial Protocol for a Stationary Cycling Intervention. BMC Pediatrics, 7:14, 2007.