about_learning_facilities.jpg about_the_center.jpg alumni.jpg central_market.jpg continuing_ed.jpg facts_history.jpg faculty_practice.jpg

Carolee Winstein

Dr. Carolee Winstein, PhD, is Professor of Biokinesiology and Physical Therapy and Associate Professor of Neurology and Director of the Motor Behavior and Neurorehabilitation Laboratory at USC. Dr. Winstein is currently Project Director/PI on the DOE/NIDRR funded study Optimizing Participation Through Technologies (OPTT) - RERC for Successful Aging With Disability and Co-Principal Investigator on the NIH/NINDS funded study The Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (I-CARE). She currently serves on the Advisory Board of the NIDRR-funded Rehabilitation Engineering and Research Center in Chicago, and the National Advisory Board on Medical Rehabilitation Research for NIH/NCMRR. She has received several awards from the APTA, including the Eugene Michels New Investigator Award and the Marion Williams award for Research in Physical Therapy, and was elected a Catherine Worthingham Fellow of the APTA.

Positions & Honors

Positions
2005-present Professor, Division of Biokinesiology and Physical Therapy, University of Southern California
2003-present Director, Motor Behavior and Neurorehabilitation Laboratory, University of Southern California
2000-present Associate Professor, Dept of Neurology, Keck School of Medicine, University of Southern California
1996-2004 Associate Professor, Department of Biokinesiology and Physical Therapy, University of Southern California
1990-1996 Assistant Professor, Department of Biokinesiology and Physical Therapy, University of Southern California
1988-1989 Postdoctoral Research Associate, Speech and Motor Control Labs, Waisman Center on Mental Retardation and Human Development, University of Wisconsin, Madison

Selected Honors & Awards
2006 11th John Maley Lecturer, "Patient-Centered Practice," Selected by the Board of Directors, American Physical Therapy Association
2006 Marion Williams award for Research in Physical Therapy, American Physical Therapy Association
2005-2009 National Advisory Board on Medical Rehabilitation Research (NABMRR)
2003 Elected Catherine Worthingham Fellow, American Physical Therapy Association
2002-2007 Advisory Board, NIDRR funded Rehabilitation Engineering and Research Center, MARS, RIC, Chicago, IL
1998 Research Award, Neurology Section, American Physical Therapy Association
1997-2003 Editorial Board Member, Physical Therapy

Education

Waisman Center, Univ. of Wisconsin, Madison Postdoc 1988-1989 Behavioral Neuroscience
University of California, Los Angeles Ph.D. 1988 Kinesiology
University of Southern California M.S. 1984 Physical Therapy
University of California, San Francisco B.S./Certificate 1973 Physical Therapy
University of California, Los Angeles B.A. 1972 Kinesiology/Psychology

Current Research Support

DoE/NIDRR H133E080024
Project Director/PI: Winstein 10/01/08 – 9/30/13
Optimizing Participation Through Technologies (OPTT) - RERC for Successful Aging With Disability
The primary objective of OPTT-RERC is to enhance the lives of individuals aging with and into disability through: (a) development and delivery of cutting-edge technologies for identification, evaluation and rehabilitation of motor processes that facilitate or impede functional performance, employment and community participation for the intended beneficiaries; (b) employment of state of the art data management, dissemination, and performance evaluation techniques to ensure that the knowledge and products emergent from the RERC are accessible for all intended beneficiaries; (c) assembly of a multidisciplinary team of experts in clinical rehabilitation, engineering, gerontology, along with a select group of technology partners, and disability advocates to ensure that OPTT-RERC's short and long-term outcome goals are successfully implemented; and (d) alignment of the clinical and technological strengths of several area programs into an integrated infrastructure to provide training opportunities for future rehabilitation researchers.
Role: Project Director/PI

NIH/NINDS/NICHD U01 NS056256
PIs: Winstein, Dromerick, Wolf 8/10/08 - 7/31/13
The Interdisciplinary Comprehensive Arm Rehabilitation Evaluation (I-CARE)
The primary objective of I-CARE is to improve outpatient therapy for arm paresis after stroke. We will conduct a Phase III, single blind, multi-center, randomized control trial to investigate the effectiveness of ASAP (Accelerated Skill Acquisition Program), a focused, intense, evidence-based, upper extremity rehabilitation program. ASAP combines aspects of constraint-induced therapy, skill-based/impairment-mitigating task-specific training with embedded motivational enhancements and includes 30 hours of one-on-one therapy initiated during the early post-acute outpatient interval (1-3 months) after stroke.
Role: Principal Investigator

NSF IIS-07136977
PI: Mataric 8/15/07 - 7/31/10
HRI: Personalized Assistive Human-Robot Interaction: Validation in Socially-Assisted Post-Stroke Rehab
This interdisciplinary proposal identifies a specific set of HRI research questions in socially assistive robotics, the study of robotic systems capable of providing guidance through social rather than physical interaction. The research foci are: embodiment, personality, empathy, and adaptability toward the development of an assistive HRI model for customized time-extended interaction. The proposed research is grounded in the rehabilitation domain with emphasis on post-stroke recovery, where personalized and dedicated care provides supervision, motivation, and training and where assistive HRI can play a key role.
Role: Co-Principal Investigator

NIH P20 Exploratory Centers for Interdisciplinary Research
PI: McNeill 9/28/04 - 6/30/09
New Directions for Stroke Rehabilitation
This interdisciplinary proposal identifies a specific set of HRI research questions in socially assistive robotics, the study of robotic systems capable of providing guidance through social rather than physical interaction. The research foci are: embodiment, personality, empathy, and adaptability toward the development of an assistive HRI model for customized time-extended interaction. The proposed research is grounded in the rehabilitation domain with emphasis on post-stroke recovery, where personalized and dedicated care provides supervision, motivation, and training and where assistive HRI can play a key role.
Role: Co-Principal Investigator

Selected Publications

  1. Chen SY, Winstein CJ. (2009). A systematic review of voluntary arm recovery in hemiparteic stroke: critical predictors for meaningful outcomes using the international classification of functioning, disability, and health. J. Neurol Phys Ther, 33(1):2-13.
  2. Harvey RL, Winstein CJ. (2009). Design for the Everest randomized trial of cortical stimulation and rehabilitation for arm function following stroke. Neurorehabil Neural Repair, 23 (1):32-44.
  3. Lin CH, Fisher BE, Winstein CJ, Wu AD, Gordon J. (2008) Contextual interference effect: elaborative processing or forgetting-reconstruction? A post hoc analysis of transcranial magnetic stimulation-induced effects on motor learning. J Motor Behavior, 40(6): 578-86.
  4. Park SW, Wolf SL, Blanton S, Winstein C, Nichols-Larsen DS. (2008). The EXCITE trial: Predicting a clinically meaningful motor activity log outcome. Neurorehabilitation and Neural Repair. 22(5): 486-93.
  5. Tretriluxana J, Gordon J, Winstein CJ. (2008). Manual asymmetries in grasp pre-shaping and transport-grasp coordination. Experimental Brain Res. 188(2): 305-15.
  6. Wolf SL, Winstein CJ, Miller PJ, Thompson PA, Taub E, Uswatte G, Morris D, Blanton S, Nichols-Larsen D, Clark PC. (2008). Retention of upper limb function in stroke survivors who have received constraint-induced movement therapy: the EXCITE randomized trial. The Lancet Neurology, 7(1): 33-40.
  7. Onla-or, P. & Winstein, C.J. (2008). Determining the optimal challenge point for motor skill learning in adults with moderately severe Parkinson’s Disease. Neurorehabil Neural Repair, 22(4): 385-95.
  8. Winstein C, Pate P, Ge T, Ervin C, Baurley J, Sullivan KJ, Underwood SJ, Fowler EG, Mulroy S, Brown DA, Kulig K, Gordon J, Azen SP & Physical Therapy Clinical Research Network. (2008). The Physical Therapy Clinical Research Network (PTClinResNet): Methods, efficacy and benefits of a rehabilitation research network. Am J Physical Medicine & Rehabil. 87(11): 937-50
  9. Winstein, C.J., Bentzen, K.R., Boyd, L., Schneider, L.S. (2007). Does Donepezil, a cholinesterase inhibitor, benefit declarative and non-declarative processes in mild to moderate Alzheimer’s disease? Current Alzheimer Research, 43: 273-6
  10. Sullivan KJ, Brown DA, Klassen T, Mulroy S, Ge T, Azen SP, Winstein CJ, Physical Therapy Clinical Research Network (PTClinResNet) (2007). Effects of task-specific locomotor and strength training in adults who were ambulatory after stroke: results of the STEPS randomized clinical trial. Phys Ther, 87: 1580-602.