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Reading New Generations of DNA Sequence

Center for Excellence in Research Advancement Workshops

• When: Wednesday, November 11, 2009 : 12:00pm to 1:00pm
• Location: University Park Campus, Credit Union Building, Room 329
• Audience: Faculty
• Sponsored By: Office of the Provost
• Organizer: usccer@usc.edu, (213) 740-6709
• E-mail: usccer@usc.edu
• Due to limited space, RSVP is required.
• RSVP: usccer@usc.edu

DNA sequences are determined from gathering "reads," segments of sequence located randomly on the target genome.

Faster technology for producing the reads has been developed which makes the previous computational methods obsolete. Eulerian graphs provide the basis for handling the new data. Reads are compared pairwise for overlaps, the overlap numbers are processed for overlap groups which are mutually consistent, and then these are aligned to estimate the underlying letter sequence.

 

Last updated: Tuesday, January 27, 2009, 3:28pm PDT