• Research
• Centers and Facilities

Genomics

Affymetrix Core Laboratory

The Affymetrix Core provides genomic analyses, predominantly using Affymetrix GeneChips, for: Whole transcriptome gene expression profiling, for human and mouse, and any other organism for which Affymetrix microarrays are available; p53 mutation analysis, using Affymetrix p53 GeneChips; and whole genome high density SNP analyses, using 10K, 100K SNP and 500K arrays. Visit Site

USC/CHLA Affymetrix MicroArray Core Laboratory
Betty Schaub
Pathology & Laboratory Medicine
4650 Sunset Blvd, MS#103
Los Angeles, CA, 90027
(323)-669-2234
BSchaub@chla.usc.edu

Custom Microarray Core

The Microarray Core supports all aspects of expression studies by microarrays: RNA extraction from tissue and cell culture, cDNA synthesis, cRNA amplification, probe labeling, hybridization to the microarray printed slides, scanning of the slides and analysis of the results. Visit Site

Nancy Hsu
Custom Microarray Core
Institute For Genetic Medicine
2250 Alcazar St. CSA 219
Los Angeles CA. 90033
323-442-1175
uscmcf@usc.edu

DNA Sequencing and Genetic Analysis Core Facility

The Cell and Neurobiology DNA Sequencing Core carries out DNA sequencing reactions. Major instruments include a Perkin-Elmer Applied Biosystems GeneAmp PCR System 9700 thermal cycler and an ABI PRISM 310 Genetic Analyzer. Visit Site

Mary D. Allen Laboratories for Vision Research
Doheny Eye Institute Vision Research Center
DVRC Room 410
University of Southern California
Los Angeles CA 90089
323-442-6686

General and Clinical Research Center Standard and Molecular Laboratory Core

The General and Clinical Research Center Standard and Molecular Laboratory Core provides customized specimen processing services and offers a range of research quality tests, including: DNA extractions; lipids, hormones, peptides, and diabetes tests; DNA and/or RNA extraction from tissues or cell lines; establishment of EBV-immortalized cell lines; DNA sequencing; semi-automated genotyping using florescent-labeled dye technologies; and can develop additional assays for multi-user needs. Visit Site

Dr. Carole A. Spencer
Director, GCRC Core Laboratory
LAC/USC Medical Center
1200 N. State Street
Ward 6800
Los Angeles, CA 90033
323-224-7132
cspencer@hsc.usc.edu

Microchemical Core

The Microchemical Core Facility provides DNA Sequencing, Oligonucleotide Synthesis, Protein Sequencing and Peptide Synthesis services to researchers at USC and other institutions. Visit Site

Matthew Gray, Program Manager
Microchemical Core Facility
University of Southern California
1441 Eastlake Ave, NOR 5338
Los Angeles, CA 90033
323-865-0541
graymt@usc.edu

Norris Center Genomics Core

The Genomics Core Facility performs high throughput analyses of genetic (polymorphism/mutation) and epigenetic variations (DNA methylation) that underlie predisposition and progression to cancer. The Core uses the latest technology to evaluate primarily genetic variations for association studies using single nucleotide polymorphisms (SNPs). Visit Site

Loreall Pooler, Laboratory Manager
Genomics Core
USC Genomics Center
Zilkha Neurogenetic Institute
1501 San Pablo St., Rm 301
Los Angeles, CA 90033
323-442-3629
CoreGenomics@ccnt.hsc.usc.edu

Proteomic Core Facility

The Proteomic Core Facility uses advanced mass spectrometry to measure the molecular mass of proteins of interest. Its resources include a ThermoFinnigan LCQ Deca XP Plus ion trap with ProteomeX system; ThermoFinnigan TSQ-7000 triple quadrupole; and Shimadzu Kratos Analytical Axima-CFR MALDI-TOF. Visit Site

Proteomic Core Facility
Rodrigo Aguilera
PSC 306B
1985 Zonal Avenue
Los Angeles, California 90033
(323) 442-1782 or (323) 442-1780
rodrigo.aguilera@usc.edu

Last updated: Thursday, July 17, 2008, 1:33pm PDT