Edward D. Crandall , MD, PhD

Research Interests

Dr. Crandall has authored numerous peer reviewed articles on cardiopulmonary biology. His specific research interests are in the regulation of the differentiation and transport properties of alveolar epithelial cells.

Clinical Interests

Critical Care Medicine
Pulmonary Disease

Degrees

Northwestern University, PhD, 1964
Northwestern University, MS, 1962
University of Pennsylvania, MD, 1972

Internships

Hospital of the University of Pennsylvania, 1972 - 1973

Residencies

Hospital of the University of Pennsylvania, 1973 - 1974

Fellowships

Hospital of the University of Pennsylvania, 1974 - 1976

Board Certification

American Board of Internal Medicine, 1975
American Board of Internal Medicine, Pulmonary Disease, 1976

Memberships

American Thoracic Society
American Society for Clinical Investigation
American Society for Cell Biology
American Assoc. for the Advancement of Science
American College of Chest Physcians
American Federation for Medical Res.
American Heart Association
American Instiute of Chemical Engenering
American Physiological Society
California Thoracic Society

Clinical Affiliation

USC Care Medical Group
USC University Hospital
USC/Norris Cancer Hospital

Selected Publications

Borok Z, Li X, Fernandes VFJ, Ann DK, Crandall ED: Differential regulation of rat aquaporin-5 promoter/enhancer activities in lung and salivary epithelial cells. J Biol Chem 275:26507-26514, 2000.

Kemp PJ, Kim KJ, Borok Z, Crandall ED: Re-evaluating the Na+ conductance of adult alveolar type II pneumocytes: evidence for the involvement of cGMP-activated cation channels. J Physiol (Lond) 536:693-701, 2001.

Borok Z, Liebler JM, Lubman RL, Foster MJ, Zhou B, Li X, Zabski SM, Kim KJ, Crandall ED: Sodium transport proteins are expressed by rat alveolar epithelial type I cells. Am J Physiol 282:L599-L608, 2002.

Kim KJ, Matsukawa Y, Yamahara H, Kalra VJ, Lee VHL, Crandall ED: Absorption of intact albumin across rat alveolar epithelial cell monolayers. Am J Physiol 284:L458-L465, 2003.

Kim KJ, Fandy TE, Lee VHL, Ann DK, Borok Z, Crandall ED: Net absorption of IgG via FcRn-mediated transcytosis across rat alveolar epithelial cell monolayers. Am J Physiol 287:L616-L622, 2004.

Kim KJ, Borok Z, Ehrhardt C, Willis B, Lehr CM, Crandall ED: Estimation of paracellular conductance of primary rat alveolar epithelial cell monolayers. J Appl Physiol 98:138-143, 2005.