USC/Norris Neuro-Oncology Program

Innovative approach to Cancer Management

Clinical Trials
The following clinical trials, for the treatment of various brain and spinal tumor conditions, are available for your participation. Those marked with an asterisk (*) are done in conjunction with either the Southwest Oncology Group (SWOG) or the Radiation Oncology Group (RTOG), both national multi-institutional cooperative groups.

Primary Brain and Spine Tumors
Glioblastoma
• Phase III Multicenter Study of Intratumoral/Interstitial Therapy with TransMID compared to Best Standard Care in Patients with Progressive and/or Recurrent, Non-Resectable Glioblastoma Multiforme.
• Phase III Randomized Evaluation of Convection Enhanced Delivery of IL13-PE38QQR Compared to Gliadel Wafer with Survival Endpoint in Glioblastoma Multiforme Patients at First Recurrence

Anaplastic Oligodendroglioma
• Phase I/II Randomized Trial with Radiation Therapy/Temozolomide vs. Radiation Therapy/Temozolomide for anaplastic astrocytoma.*
Neuroectodermal Tumors (PNET)

Meningioma

Phase II Irinotecan HCl Study in Recurrent Meningiomas


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