In many situations, biostatistical methodology has been developed because of the unique characteristics of the designs and/or data arising from a medical research project. The Statistical Consultation and Research Center (SCRC) provides opportunities for faculty and graduate students to develop independent research that expands biostatistical knowledge, including such projects as:

EVALUATING CORONARY LESIONS USING NEURAL NETWORKS (NIH R03-HL-55150) employs and evaluates the ability of neural networks to serve as clinical tools for predicting clinical coronary events.

CORRELATES OF ANGIOGRAPHIC CHANGES AND CORONARY EVENTS (NIH R03-HL-54532) evaluates invasive (coronary angiography) and non-invasive (common carotid artery IMT) surrogate outcome measures for clinical coronary events by comparing two independent clinical trials with different modes of lipid-lowering therapy, comparably conducted, with similar outcome measures and analyzes the predictive power of all three of the 2-year surrogate endpoints for clinical coronary events.

FULLY INTEGRATIVE RESEARCH SYSTEM TECHNOLOGY (FIRST, NIH M01-RR-00043) is a supplemental grant to the GCRC to develop a multi-centered, Web-based, data management, analysis and reporting system appropriate for General Clinical Research Center (GCRC) and SCRC investigations.