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  »Alzheimer's Disease Neuroimaging Initiative (ADNI)
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What is this study about?
This study evaluates whether imaging studies and biomarker tests, together with measurements of memory, thinking and daily functioning, will be useful in identifying and treating early stage Alzheimer's disease.

How will the study be conducted?

This study will look at three different groups of volunteers:

  • Normal Control group: 200 volunteers with no apparent memory problems that will be studied for 36 months
  • MCI Group: 400 volunteers with mild memory problems (referred to in this study as “mild cognitive impairment” - MCI) that will be studied for 36 months and
  • Alzheimer’s disease group: 200 volunteers with mild Alzheimer’s disease that will be studied for 24 months.

What will participation in this study entail?
Your participation will involve at least 8 clinic visits as well as telephone contacts during a period of 24 – 36 months. You will be asked to give blood samples, to take tests of memory, thinking skills, daily functioning and behavior, and to have repeated Magnetic Resonance Imaging (MRI) scans of your brain. You may also be asked to have repeated Positron Emission Tomography (PET) scans of your brain and/or spinal taps

Who is eligible to participate in this study?
You can be eligible for this study if you are between 55 to 90 years old, can speak English or Spanish fluently, have atleast 6 grades education or work history, good general health, and not enrolled in other trials or studies. If you are a woman, you must also be sterile or two years past childbearing potential.

How can I enroll in this study?
This study is currently enrolling volunteers. If interested, please contact:
Maya Slowinska (
University of Southern California Keck School of Medicine
Phone: (323) 442-7600

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