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Why is this study being done ?
Genes exert a powerful influence on the risk of Alzheimer disease. Three genes have been discovered for the rare forms of Alzheimer's disease that begin in mid-life (ages 40-60 years). Scientists estimate that a half a dozen genes for Alzheimer's disease are yet to be discovered.

What will participation in this study entail?

For both of the siblings enrolled in the study, we seek to obtain:

  • Detailed family and medical history
  • Memory testing in person or over the phone
  • History of everyday activities and function
  • Magnetic resonance imagine (MRI) of the head
  • Blood sample for white cells containing DNA

Who is eligible to participate in this study?

We are looking for:

  • one sibling who has progressive memory loss due to Alzheimer's disease AND
  • one sibling who has intact memory abilities
  • 60 years or older

How can I enroll in this study?
This study is currently enrolling volunteers. If interested, please contact:
Maya Slowinska (
University of Southern California Keck School of Medicine
Phone: (323) 442-7600

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