Shared research core facilities and resources provide for centralized support of technologies essential to modern biomedical research and also offer a wide variety of instrumentation, services, and expertise to support the research efforts of the faculty. Please click the fold-down menus below for a short description of shared research core facilities and resources housed and administered at the Keck School of Medicine, as well as links to their websites.
Please click the following link to access the Centers & Facilities page on the University Research website. This provides a comprehensive list of all USC core facilities
Please visit the Los Angeles Basin Clinical & Translational Science Institute’s Translational Toolbox of Technologies & Core Facilities webpage for a comprehensive listing of shared research facilities and resources across USC and its partner institutions that are available to Keck School faculty members
The Biostatistics Core Services - This resource provides statistical support to clinical, basic science and cancer cause and prevention investigators. This support may range from simple advice, to participating in the design of the research project, to carrying out aspects of the data management and statistical analysis of a project. This resource is housed within the Norris Comprehensive Cancer Center.
Statistical Consultation & Research Center - The Statistical Consultation and Research Center (SCRC) is an Organized Research Unit at the University of Southern California which integrates statistical, epidemiological and computing resources and offers them to professionals conducting clinical, biomedical and translational research. The SCRC consists of a team of statisticians, epidemiologists, database developers, programmers, project coordinators and data managers that provides an optimal structure to assist both the public and private sectors in carrying out clinical and prevention trials, observational and retrospective studies, cross-sectional and longitudinal surveys and translational research. Members of the SCRC are co- investigators on a range of studies in atherosclerosis, cancer, diabetes, neuroscience, ophthalmology, stroke rehabilitation interventions, lifestyle redesign interventions and alternative medicine.
Clinical Investigations Support Office - This office provides centralized administration for protocol development, review, prioritization, regulatory compliance, study conduct and monitoring, and quality assurance. It is comprised of a centralized Protocol Administration Unit and a Research Nursing/Data Management Unit. The resource is housed within the Norris Comprehensive Cancer Center.
General Clinical Research Center - The Keck School of Medicine is home to the nation’s largest NIH-funded General Clinical Research Centers. The GCRC provides research services and support for a variety of clinical investigations – from diabetes to seizure disorders.
Cell and Tissue Imaging Core Facility – The primary function of this core facility is to provide assistance and training in the operation of a wide variety of instrumentation for cell and tissue imaging. The core facility also offers support for specimen preparation, thin sectioning techniques, embedding procedures, cryosectioning techniques, photography, digital photomicroscopy and photomicrography and computer aided graphics. This facility is housed within the Department of Ophthalmology and the Doheny Eye Institute and is co-administered by the Norris Comprehensive Cancer Center.
Molecular Imaging Center – The USC Molecular Imaging Center offers accessibility to a wide variety of state-of-the-art imaging instrumentation. The core’s mission is to increase awareness and accessibility for all scientists, as well as assist investigators with imaging research projects. This facility is administered by the department of radiology.
Bioreagents & Cell Culture Core Facility – This core facility supports cancer related research that requires in vitro experiments, provides reagents for cell culture and prepares bioreagents that are produced by cells grown in the facility. The core grows suspension cultures of hybridoma cells in large quantities and produces purified monoclonal antibodies using a New Brunswick BioReactor, providing for substantial savings to the investigator. The core is in the process of developing and evaluating lipofectin preparations for cell transfection at highly reduced costs. Additional available services include the preparations of specialized serum products, LB medium, matrix coated culture dishes, and AmpicillinR plates. Studies will be conducted to evaluate the feasibility of producing recombinant proteins, cytokines and growth factors. This facility is housed within the Norris Comprehensive Cancer Center.
Flow Cytometry and Immune Monitoring Core – This core offers advice, technical support and equipment for performing flow cytometry and immune monitoring. The facility is housed within the Norris Comprehensive Cancer Center.
The Non-Parenchymal Liver Cell Core – This core provides freshly isolated or cultured Kupffer, hepatic and sinusoidal endothelial cells (KC: hepatic macrophages), hepatic stellate cells (HSC) and sinusoidal endothelial cells (SEC) from normal rats or rat models of liver injury. This facility is housed within the department of pathology and managed by the Southern California Research Center for ALPD & Cirrhosis.
DNA Core Facility - This core provides DNA sequencing, oligonucleotide synthesis, protein sequencing and peptide synthesis services to researchers at USC and other institutions. The facility is housed within the Norris Comprehensive Cancer Center.
Genomics Core Facility - This core performs high throughput analyses of genetic (polymorphism/mutation) and epigenetic variations (DNA methylation) that underlie predisposition and progression to cancer. The facility is housed within the Norris Comprehensive Cancer Center.
Proteomics Core Facility – Established in 2008, this core facility provides services associated with the technologies of high-sensitivity and high-resolution mass spectrometry for protein and peptide analysis. The facility is housed in department of molecular microbiology & immunology space and is administered by the department of medicine.
Microchemical Core Facility - This facility was established in 1993 to provide high-quality embryo and stem cell manipulation, microinjection and related services to the USC community, as well as outside researchers. The core handles the production of transgenics, gene targeting and the production of knockouts, construction of targeting vector design, preparation of DNA for injection and in vitro fertilization, re-derivation, as well as cryopreservation.
Please click the fold-down menu below for a description of USC’s five health sciences libraries, as well as links to their websites.
Norris Medical Library – This Library is the largest of five medical libraries on the Health Sciences Campus (HSC). It has an extensive collection on all aspects of biomedicine and health care and is the main library of the Health Sciences Campus. The Norris offers a number of services beyond its extensive collection of medical books and journals, including its own Web site, access to online electronic journals, a learning resources center, a computer lab and classroom, and workshops. Keck School faculty, students and staff may access all of the HSC libraries, although borrowing privileges, hours and rules vary.
Wilson Dental Library - The Wilson Dental Library, located on the University Park Campus, has an extensive collection of materials relating to dentistry and oral health as well as many services for its users.
Doheny Eye Institute Library - The DEI has a small lending library focused exclusively on ophthalmology and vision.
LAC+USC Medical Center Library - The General Hospital houses a lending and reference library on medical sciences for students, house staff and physicians.
USC-University Hospital Library - USC University Hospital has a small reference-only library for students, house staff, physicians and patients.
Ovid – Electronic Search Tool
HELIX - Catalog of the USC Health Sciences Libraries
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