Giske Ursin , M.D., Ph.D.

Research Interests

Dr. Ursin's research focuses on the epidemiology of breast cancer and other hormone-dependent cancers. She is particularly interested in the role of hormones and hormone metabolism in cancer etiology, gene-environment interactions, as well as how mammograms can be used in the prevention of breast cancer.

Clinical Interests

Epidemiology of female cancers
hormones, gene-environment interactions.
prostate cancer, benign prostatic hyperplasia

Degrees

University California, Los Angeles, PHD, 1992
University of California, Los Angeles, MPH, 1985
University of Bergen, Norway, MD, 1987

Internships

L, 1987 - 1989

Fellowships

Norwegian Research Council, Norway. , 1989 - 1992
University of Southern California, 1992 - 1995

Professional Experience

Visiting scientist, Division of Cancer Etiology, NCI, Bethesda, Maryland, 1990 - 1991

PUBLICATIONS

Maskarinec G, Lyu L-C, Meng L, Theriault A, Ursin G. Determinants of mammographic densities among women of Asian, Native Hawaiian, and Caucasian ancestry. Ethnicity & Disease 2001; 11:44-50 .

Ursin G, Wilson M, Henderson BE, Kolonel LN, Monroe K, Lee HP, Seow A, Yu MC, Stanczyk FZ, Gentschein E. Do urinary estrogen metabolites reflect the differences in breast cancer risk between Singapore Chinese and U.S.African American and White women? Cancer Research 2001; 61:3326-3329.

Ursin G, Parisky YR, Pike MC, Spicer DV. Mammographic density changes during the menstrual cycle. Cancer Epidemiology Biomarkers and Prevention 2001; 10:141-142.

Maskarinec G, Meng L, Ursin G. Ethnic differences in mammographic densities. Int J Epidemiol 2001 (in press).

Ursin G, London S, Yang D, Tseng CC, Pike MC, Bernstein L, Stanczyk FZ, Gentschein E. Urinary 2-Hydroxyestrone/16-Hydroxyestrone Ratio and Family History of Breast Cancer in Premenopausal Women. Breast Cancer Research and Treatment (in press).

Gram IT, Ursin G, Spicer DV, Pike MC. Reversal of Gonadotropin Releasing Hormone agonist based regimen induced changes in mammographic densities. A randomized clinical trial-phase1. Cancer Epidemiology Biomarkers & Prevention (in press)

Ursin G, Aragaki CA, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW. Oral contraceptives and premenopausal bilateral breast cancer, a case-control study. Epidemiol 1992;3:414-419.

Ursin G, Ziegler RG, Subar AF, Graubard BI, Haile RW, Hoover R. Dietary patterns associated with a low-fat diet in the National Health and Examination Follow-up Study: Identification of potential confounders for epidemiologic analyses. Am J Epidemiol 1993;137:916-927.

Spicer DV, Ursin G, Parisky YR, Pearce JG, Shoupe D, Pike A, Pike MC. Changes in mammographic densities induced by a hormonal contraceptive designed to reduce breast cancer risk. J Natl Cancer Inst 1994;86:431-436.

Ursin G, Bernstein L, Pike MC. Breast cancer. Cancer Surveys 1994;19/20:241-264.

Ursin G, Spicer DV, Pike MC. Contraception and cancer prevention. Adv Contra Deliv Syst 1994;10:369-386.

Ursin G, Peters RK, Henderson BE, d'Ablaing G, Monroe KR, Pike MC. Oral contraceptive use and adenocarcinoma of the cervix. Lancet 1994;344:1390-1394.

Ursin G, Paganini-Hill A, Siemiatycki J, Thompson WD, Haile RW. Body weight, body mass index and premenopausal bilateral breast cancer: results from a case-control study. Breast Cancer Res Treat 1994;33:75-82.

Ursin G, Longnecker MP, Haile RW, Greenland S. A meta-analysis of body mass index and risk of premenopausal bilateral breast cancer. Epidemiol 1995;6:137-141.

Haile RW, Witte JS, Ursin G, Siemiatycki J, Bertolli J, Thompson WD, Paganini-Hill A. A case-control study of reproductive variables, alcohol, and smoking in premenopausal bilateral breast cancer. Breast Cancer Res Treat 1996;37:49-56.

Ursin G, Pike MC, Spicer DV, Porrath SA, Reitherman RW. Can mammographic densities predict the effect of tamoxifen on the breast? [letter] J Natl Cancer Inst 1996;88:128-129.

Ursin G, Pike MC. Correspondence re: J.Russo, A.L. Romero, and I.H.Russo, Architectural pattern of the normal and cancerous breast under the influence of parity [letter]. Cancer Epidemiol Biomark Prev 1996;5:143.

Ursin G, Pike MC, Preston-Martin S, d'Ablaing G, Peters RK. Sexual, reproductive and other risk factors for adenocarcinoma of the cervix; results from a population based case-control study Cancer Causes and Control 1996;7:391-401.

Ursin G, Pike MC, Spicer DV. A case-control study of combined continuous estrogen-progestin replacement therapy among women with a personal history of breast cancer [letter]. Menopause 1996;3:118.

Ursin G, Henderson BE. Breast Cancer Prevention in African-American Women [editorial]. J Natl Cancer Inst 1996;88:1332-1333.

Byrne C, Ursin G, Ziegler RG. A comparison of food habit and food frequency data as predictors of breast cancer in the NHANES I/NHEFS cohort. J Nutr 1996;126:2757-2764.

Witte JS, Ursin G, Siemiatycki J, Thompson WD, Paganini-Hill A, Haile RW. Diet and premenopausal bilateral breast cancer: a case-control study. Breast Cancer Res Treat 1997;42:243-251.

Ursin G, London S, Stanczyk FZ, Gentzschein E, Paganini-Hill A, Ross RK, Pike MC. A pilot study of urinary estrogen metabolites (16a-OHE1 and 2-OHE1) in postmenopausal women with and without breast cancer. Environ Health Perspect 1997;105:601-605.

Ursin G, Henderson BE, Haile RW, Zhou N, Diep A, Bernstein L. Does oral contraceptive use increase the risk of breast cancer more in women with BRCA1/BRCA2 mutations than in other women? Cancer Res 1997;57:3678-3681.

Vatten LJ, Ursin G, Ross RK, Stanczyk F, Lobo F, Harvei S, Jellum E. 5-a androgens in serum and the risk of prostate cancer. Cancer Epidemiol Biomark Prev 1997;6:967-969.

Ursin G, Astrahan MA, Salane M, Parisky YR, Pearce JG, Daniels J, Pike MC, Spicer DV. The detection of changes in mammographic densities. Cancer Epidemiol Biomark Prev 1998;7:43-47.

Ursin G, Bernstein L, Sullivan-Halley JA, Hanisch R, Ross RK. Oral contraceptive use and breast cancer risk in young women. Breast Cancer Res Treat 1998;50:175-184.

Ursin G, Ziegler RG, Pike MC, Wu AH, Nomura AMY, West DW. Breast cancer and oral contraceptive use among Asian-American women. Am J Epidemiol 1999;150:561-567.

Ursin G, London S, Stanczyk FZ, Gentzschein E, Paganini-Hill A, Ross RK, Pike MC. Urinary 2-hydroxyestrone/16a-hydroxyestrone ratio and risk of breast cancer in postmenopausal women. J Natl Cancer Inst 1999;91:1067-1072.