Childrens Hospital Gets $2.4M Grant
“We will study the impact of blood viscosity on oxygen delivery in humans with sickle cell anemia,” said Coates, the principal investigator on the NIH grant.
Childrens Hospital Los Angeles is one of a dozen Basic and Translational Research Programs studying sickle cell disease in the United States – and the only sickle cell basic program on the West Coast.
The new basic and translational project utilizes expertise from collaborators in the areas of biomedical engineering, biophysics and hematology who are working to understand the principles that regulate blood flow in patients with sickle cell disease.
Parts of the research will directly address theoretical concepts related to blood viscosity and micro vascular circulation and also will attempt to develop techniques that can be used in the clinic to directly measure the sickling process and predict sudden cardiac death.
The project is multidisciplinary, involving physicians from Childrens Hospital Los Angeles as well as members of the faculty from both the Keck School and the USC Viterbi School of Engineering. It continues a long-standing relationship between the Hemoglobinopathy Program at Childrens Hospital Los Angeles and its research counterparts at USC.
Sickle cell disease is an inherited disorder of hemoglobin that causes normally flexible red blood cells to become very rigid and obstruct blood flow leading to ischemia, organ damage and ultimately, death.
Chronic transfusions markedly reduce sickle episodes and protect against recurring stroke and acute chest syndrome.
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The Chronicle of Higher Education mentioned USC’s $6 billion fundraising campaign. The story noted that USC had already raised $1 billion in a “quiet phase,” including the $200 million naming gift from USC Trustee and alumnus David Dornsife and wife Dana Dornsife to the USC Dornsife College.
The Guardian (U.K.) highlighted two major gifts to USC in a list of the 10 biggest philanthropic benefactors in America. The list included the $200 million naming gift from USC Trustee and alumnus David Dornsife and wife Dana Dornsife to the USC Dornsife College, and the $110 million gift from USC Trustee and USC Viterbi School alumnus John Mork and wife Julie to create the USC Mork Family Scholars Program.
The New York Times featured the USC U.S.-China Institute documentary “Assignment: China — The Week that Changed the World.” The documentary, part of a series, examines media coverage of the 1972 Nixon trip that reshaped U.S.-China relations after a quarter century of isolation and hostility. “People look back now and take it for granted that the outcome was preordained,” said the institute’s Mike Chinoy, who produced the documentary. Voice of America also featured the story.
Los Angeles Times featured the Oscar Senti-meter, a tool developed by the USC Annenberg School, Los Angeles Times and IBM that analyzes thousands of tweets about the Academy Awards nominees. The story noted that Mexican actor Demian Bechir received an enormous boost on Twitter the day of the nominations, with a total of 6,893 tweets mentioning him, a 47-fold increase from the day before. The story noted the tool uses language-recognition technology developed in collaboration with USC Viterbi School’s Signal Analysis and Interpretation Lab.
The Times of India (India) featured a three-day medical emergency training workshop organized in association with USC. At the workshop, held at GCS Medical College in India, 50 doctors and more than 100 paramedics learned how to improve emergency support systems. William Mallon of the Keck School of USC said that discussion topics included the use of portable ultrasonic devices to scan patients. “The ultrasound applications help physicians make accurate and timely decisions,” he noted. Daily News & Analysis (India) also featured the workshop.
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